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Bloating clinical trials

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NCT ID: NCT05520411 Completed - Bloating Clinical Trials

Examining the Effectiveness of Digestive Enzymes at Reducing Bloating and Stomach Distension

Start date: July 1, 2022
Phase: N/A
Study type: Interventional

Flatter Me is a product that includes digestive enzymes in a way to support digestion of macronutrients and their constituents and provides herbs traditionally used for digestive health support. This trial aims to test Flatter Me against a placebo pill to examine differences in both subjective outcomes (feelings of bloating and indigestion) and changes in waist circumference (abdominal distension) after eating a test meal.

NCT ID: NCT04182178 Completed - Dysphagia Clinical Trials

Long-term Follow-up After Surgical Treatment for GERD (Gastroesophageal Reflux Disease)

Start date: August 5, 2019
Phase:
Study type: Observational

10 years of follow-up with SF-36 global (Quality of Life issues), GSRS (Gastrointestinal Symptom Rating Scale) and two reflux specific questionnaires.

NCT ID: NCT03548363 Completed - Dyspepsia Clinical Trials

Effect of Gingest on Symptoms of Dyspepsia

Start date: March 13, 2018
Phase: N/A
Study type: Interventional

This is a randomised, double-blind, placebo controlled study on the effect of Gingest (ginger root extract) on symptoms of dyspepsia in 150 participants with mild to moderate dyspepsia.

NCT ID: NCT03134469 Completed - Bloating Clinical Trials

Efficacy of Probiotics on Excessive Gas Accumulation

Start date: April 18, 2017
Phase: N/A
Study type: Interventional

Efficacy of probiotics on excessive gas accumulation

NCT ID: NCT03060746 Completed - Weight Loss Clinical Trials

Helicobacter Pylori Sample Collection Protocol Pre Therapy Subjects

Start date: February 14, 2017
Phase:
Study type: Observational

The primary objective is to obtain stool samples from pre-therapy subjects already undergoing evaluation for an H. pylori infection by upper esophagogastroduodenoscopy (EGD) and gastric biopsy.

NCT ID: NCT03060733 Completed - Weight Loss Clinical Trials

Helicobacter Pylori Sample Collection Protocol Post Therapy Subjects

Start date: February 14, 2017
Phase:
Study type: Observational

The primary objective is to obtain stool samples from post-therapy subjects already undergoing evaluation for an H. pylori infection by upper esophagogastroduodenoscopy (EGD) and gastric biopsy.

NCT ID: NCT02950012 Completed - Bloating Clinical Trials

A Study to Evaluate OPTI-BIOME™ Bacillus Subtilis MB40 on Abdominal Discomfort, Gas and Bloating in a Healthy Population

Start date: October 2016
Phase: Phase 2
Study type: Interventional

The purpose of this study is to investigate the effects of OPTI-BIOME™ (Bacillus subtilis MB40), a probiotic supplement, on bloating, gas and abdominal discomfort symptoms in otherwise healthy adults.

NCT ID: NCT02277431 Completed - Abdominal Pain Clinical Trials

Probiotic Supplementation Among Adults With Recurrent Gastrointestinal Symptoms

Start date: December 2014
Phase: Phase 2/Phase 3
Study type: Interventional

Participants experiencing recurrent gastrointestinal symptoms in this double-blind, randomized, controlled trial will receive either a commercially-available probiotic dietary supplement or placebo. The investigators hypothesize that participants in the probiotic dietary supplement group will experience greater improvement in their gastrointestinal symptoms than participants in the placebo group.

NCT ID: NCT01099696 Completed - Bloating Clinical Trials

Study to Evaluate a Probiotic in Healthy Subjects With a History of Abdominal Discomfort and Bloating

Start date: April 2010
Phase: N/A
Study type: Interventional

This is a multicenter, double-blind, randomized, placebo-controlled, 6-week study of a probiotic for abdominal discomfort and bloating in healthy subjects.

NCT ID: NCT01064661 Completed - Abdominal Pain Clinical Trials

Pilot Study Studying Physiological Effects of Probiotic Pills in Patients With Abdominal Pain/Discomfort and Bloating

Start date: February 2010
Phase: N/A
Study type: Interventional

We are conducting a study to learn if probiotics, which are live bacteria found in food like yogurt and cheese, will improve symptoms of abdominal pain. Individuals participating in this study will take probiotic pills to see if this affects the expression of certain pain receptors in the intestines that relate to pain sensation. Biopsies will be taken from the colon before subjects take the probiotic pills. Subjects will then be given one of two different types of probiotic pills to take for 3-4 weeks. After taking the supplements, more biopsies will be collected to see if any changes have taken places. This study requires one screening visit and two clinic visits to UNC hospital. Subjects will also complete daily diary cards for 2 weeks during the study to record their symptoms and also collect 2 stool samples.