Young Blind Child Melatonin Treatment Study

Status Terminated

Clinical Trial Summary

The primary goal of this study is to identify the presence of desynchronized circadian rhythms in 25 children by measuring melatonin secretion in serial blood or saliva samples, and to rule out any primary sleep disorders.

Clinical Trial Description

Subjects will complete 25-hours of hourly salivary, plasma sampling biweekly. Melatonin will be measured in urine, for children under the age of 3. Sleep and behavioral questionnaires will be completed by parents and/or teachers. This study involves an optional, 1-year melatonin treatment sub-study, in which the children will take 0.1 - 3mg daily. A second optional sub-study involves a study of the child's sleep through polysomnography, in order to identify possible sleep disorders. ;

Study Design

Related Conditions & MeSH terms

Blindness

Clinical Trial Details

NCT number	NCT00688935
Study type	Interventional
Source	Oregon Health and Science University
Contact
Status	Terminated
Phase	N/A
Start date	January 2005
Completion date	May 2015

View Details

See also
Status	Clinical Trial	Phase
Active, not recruiting	`NCT02393118` - A Study to Evaluate the BrainPort Vision Device in Individuals Blinded by Traumatic Injury	N/A
Terminated	`NCT00262509` - Emergency Egress and Information System for Persons With Vision Loss	N/A
Terminated	`NCT00691444` - Blind Child Melatonin Treatment Study	N/A
Recruiting	`NCT06237829` - Testing Tactile Aids With Blind Subjects	N/A
Completed	`NCT00829036` - Wayfinding Information Access System for People With Vision Loss	N/A
Completed	`NCT02643238` - Continued Study of Artificial Vision: Evaluation of the BrainPort® System and Investigation of Visual Ambulation	N/A
Completed	`NCT01488786` - A Study to Evaluate the BrainPort® Vision Device in Subjects Who Are Blind	N/A
Recruiting	`NCT00403143` - Do Blue-Blocking Lenses Block Blue Colour From Our Lives?	N/A
Recruiting	`NCT04725760` - Evaluation of the Efficacy of the BrainPort Vision Pro on the Performance of Daily Activities in the Profoundly Blind French Population	N/A
Recruiting	`NCT02983370` - Development of a Cortical Visual Neuroprosthesis for the Blind	N/A
Not yet recruiting	`NCT06070467` - Holistic Mixed Approaches to Capture the Real Life of Children With Rare Eye Diseases
Completed	`NCT00920231` - Computer Vision System for the Blind Veteran	Phase 1
Completed	`NCT01109576` - Workshops for Veterans With Vision and Hearing Loss	Phase 0
Terminated	`NCT00795236` - Melatonin Studies of Totally Blind Children	N/A
Terminated	`NCT00634972` - Efficient Study of ACULAR in Inhibiting Proliferative Retinopathy in Prematurity	Phase 4
Enrolling by invitation	`NCT06364605` - MySpace: the Role of Vision in Representing Space	N/A
Terminated	`NCT03913130` - Extension Study to Study PQ-110-001 (NCT03140969)	Phase 1/Phase 2
Not yet recruiting	`NCT05806684` - Hyperbilirubinemia and Retinopathy of Prematurity in Preterm Infants: a Retrospective Study.
Completed	`NCT03753893` - Ocular Manifestations in Rheumatic Diseases
Recruiting	`NCT04855045` - An Open-label, Dose Escalation and Double-masked, Randomized, Controlled Trial Evaluating Safety and Tolerability of Sepofarsen in Children (<8 Years of Age) With LCA10 Caused by Mutations in the CEP290 Gene.	Phase 2/Phase 3