Blindness Clinical Trial
Official title:
Virtual Reality Mobility Training System for Veterans With Vision Loss
This is a two-year proof-of-concept study to evaluate a new Virtual Reality (VR) "holographic" sound system for use as an audiological Orientation and Mobility (O&M) training tool
This is a two-year proof-of-concept study to evaluate a new Virtual Reality (VR)
"holographic" sound system for use as an audiological Orientation and Mobility (O&M)
training tool. This new system avoids the limitations of other technologies (i.e., binaural
recordings and existing VR sound systems) that have been employed with limited success for
audiological training. Four advancements in the state-of-the-art represented by this new
holographic system provide new promise for audiological O&M training. First, unlike binaural
systems, the new system allows the person to move their head in a natural fashion to
localize sounds. Second, a spherical microphone array is used to record sound environments
so as to retain the direction from which each ambient sound originated. When these recorded
sound environments are later presented through head-tracking headphones in a VR environment,
real-time software maintains the directionality of the sound so that it remains true no
matter how the person moves or turns their head. Third, this new system models the actual
physical acoustic structure of each person's head and ears to present sounds as they would
be heard by that particular person in the recorded setting. Fourth, this system uses
software algorithms to isolate specific sounds (i.e., of a moving vehicle) so that during
virtual playback, these sounds can be inserted into the virtual sound field at will and in a
customizable fashion to create truly unique and flexible virtual sound presentations.
There are two study hypotheses. First, when using sounds to negotiate traffic intersections,
skills employed by experienced travelers in real environments will readily transfer to the
proposed VR environment to the extent that audiological tasks performed in real environments
are just as easily performed in the VR environment. Second, when the VR environment is
enhanced to emphasize critical sound cues and eliminate distracting or confusing noises and
sounds, performance by skilled travelers in the VR environment will be significantly better
than in the actual environment.
The objectives are to: (1) adapt the existing spherical microphone array and digital
recording software algorithms to best suit the capture of critical intersection sounds used
for intersection negotiations; (2) develop software algorithms to deconstruct intersection
sounds, isolating each sound for the VR construction of specific environments of varying
complexity; (3) determine the level of sound detail necessary for negotiating intersections
successfully; (4) expand the existing system to obtain the desired level of detail; (5)
develop software to provide the ability to control the relative emphasis of a variety of
sound elements being presented so as to simplify the auditory task; and (6) employ study
participants to compare performance in the VR environment with outdoor performance.
Once validated, this system should be able to: (1) leverage instructor time by providing
students with an effective means of practicing audiological skills on their own, (2) provide
instructors with a means of introducing concepts in a graduated learning sequence that is
not dependent on the happenstance availability of specific sounds and conditions found in
real environments, and (3) provide audiological training for environments not located in the
vicinity of the training site, but which do represent the veteran's home community.
Research will be conducted in collaboration with investigators in the Perceptual Interfaces
and Reality Laboratory (PIRL) at the University of Maryland who initially conceived and
developed this holographic VR sound system.
COMPARISONS: Outdoor O&M training exclusively
;
Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label
Status | Clinical Trial | Phase | |
---|---|---|---|
Active, not recruiting |
NCT02393118 -
A Study to Evaluate the BrainPort Vision Device in Individuals Blinded by Traumatic Injury
|
N/A | |
Terminated |
NCT00262509 -
Emergency Egress and Information System for Persons With Vision Loss
|
N/A | |
Terminated |
NCT00691444 -
Blind Child Melatonin Treatment Study
|
N/A | |
Recruiting |
NCT06237829 -
Testing Tactile Aids With Blind Subjects
|
N/A | |
Completed |
NCT00829036 -
Wayfinding Information Access System for People With Vision Loss
|
N/A | |
Completed |
NCT01488786 -
A Study to Evaluate the BrainPort® Vision Device in Subjects Who Are Blind
|
N/A | |
Completed |
NCT02643238 -
Continued Study of Artificial Vision: Evaluation of the BrainPort® System and Investigation of Visual Ambulation
|
N/A | |
Recruiting |
NCT00403143 -
Do Blue-Blocking Lenses Block Blue Colour From Our Lives?
|
N/A | |
Recruiting |
NCT06451172 -
Novel Antisense Oligonucleotide Eye Drops for Treating Antibiotic-Resistant Bacterial Keratitis
|
Early Phase 1 | |
Recruiting |
NCT04725760 -
Evaluation of the Efficacy of the BrainPort Vision Pro on the Performance of Daily Activities in the Profoundly Blind French Population
|
N/A | |
Recruiting |
NCT02983370 -
Development of a Cortical Visual Neuroprosthesis for the Blind
|
N/A | |
Not yet recruiting |
NCT06070467 -
Holistic Mixed Approaches to Capture the Real Life of Children With Rare Eye Diseases
|
||
Completed |
NCT00920231 -
Computer Vision System for the Blind Veteran
|
Phase 1 | |
Completed |
NCT01109576 -
Workshops for Veterans With Vision and Hearing Loss
|
Phase 0 | |
Terminated |
NCT00795236 -
Melatonin Studies of Totally Blind Children
|
N/A | |
Terminated |
NCT00634972 -
Efficient Study of ACULAR in Inhibiting Proliferative Retinopathy in Prematurity
|
Phase 4 | |
Enrolling by invitation |
NCT06364605 -
MySpace: the Role of Vision in Representing Space
|
N/A | |
Terminated |
NCT03913130 -
Extension Study to Study PQ-110-001 (NCT03140969)
|
Phase 1/Phase 2 | |
Not yet recruiting |
NCT05806684 -
Hyperbilirubinemia and Retinopathy of Prematurity in Preterm Infants: a Retrospective Study.
|
||
Completed |
NCT03753893 -
Ocular Manifestations in Rheumatic Diseases
|