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Blepharoptosis clinical trials

View clinical trials related to Blepharoptosis.

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NCT ID: NCT06292182 Recruiting - Clinical trials for Mitochondrial Diseases

Red Light Ptosis Proof-of-Concept

Start date: February 8, 2024
Phase: N/A
Study type: Interventional

This study tests a new treatment to help with droopy eyelids (ptosis) and eye movement problems (squint) in children and young people with genetically confirmed mitochondrial conditions - using red-light. We use a torch to shine a red light through the closed eyelid for 3 minutes a day. The study will run for 18 months. We believe that this treatment could help strengthen the muscle in the eyelid to make it easier to open the eyes, and could also help some children with squint.

NCT ID: NCT06047418 Completed - Surgical Incision Clinical Trials

Blepharoptosis in Indonesia: A 5-Year Multicenter Study on Characteristics and Surgical Evaluation

Start date: March 15, 2021
Phase:
Study type: Observational

The goal of this observational study is to learn about blepharoptosis cases in national referral hospitals in Indonesia. The main questions it aims to answer are: - How is the clinical characteristics, types, and surgical evaluations of blepharoptosis in this particular setting Participant who include in this study is a patient diagnosed with blepharoptosis cases and complete medical history from January 2016 to December 2020 across 10 tertiary hospitals in Indonesia from 5 provinces

NCT ID: NCT06040671 Recruiting - Eyelid Ptoses Clinical Trials

Objective Evaluation of the Effect of Oculoplastic Operations Using the Vectra M 3D Imaging System

Start date: May 3, 2021
Phase: N/A
Study type: Interventional

An objective assessment of that part of the spectrum of ophthalmic eyelid surgeries that focuses on correcting the position of entropy (e.g. ectropion, ptosis surgery) is very difficult - although it is possible to use different measuring parameters (distance of pupillary reflexes from the edges of the eyelid), comparing different distances on the face, exophthalmometry or the lid laxity test - the so-called snap-back test, but all these methods are based either on the subjective assessment of the examiner or on the correctness of the attached ruler, and their objectivity is therefore very low.

NCT ID: NCT05945615 Enrolling by invitation - Blepharoptosis Clinical Trials

Oxymetazoline Drops for Acquired Blepharoptosis From Synkinesis

Start date: January 11, 2024
Phase: Phase 3
Study type: Interventional

After an episode of facial paralysis, as nerves recover, they aberrantly regenerate and send additional branches to the incorrect muscles in addition to the intended muscle. This leads to what is known as Aberrant Regeneration Syndrome, Post-paralysis Synkinesis, or Nonflaccid Facial Paralysis. It is characterized by poor facial symmetry and function, hypertonic facial muscles at rest, and abnormal facial movements. One sequela is acquired blepharoptosis causing a smaller ocular aperture, visual field obstruction, cosmetic deformity, and abnormal periocular spasms. This study aims to evaluate an FDA approved medication for acquired blepharoptosis due to synkinesis/hyperkinesis as an adjunct to treatment.

NCT ID: NCT05895695 Not yet recruiting - Congenital Ptosis Clinical Trials

Levator Muscle Reaction for Unilateral Congenital Ptosis Repair as Compared to Levator Plication

Start date: July 2023
Phase: N/A
Study type: Interventional

The aim of this study was to compare the outcome of levator muscle resection with plication in mild to moderate congenital unilateral blepharoptosis.

NCT ID: NCT05890027 Recruiting - Ptosis, Eyelid Clinical Trials

Phenylephrine Versus Eyelid Taping for Muller's Muscle-Conjunctival Resection (MMCR) Evaluation

Start date: March 19, 2024
Phase: Phase 4
Study type: Interventional

This research study aims to compare whether Phenylephrine 2.5% ophthalmic eye drop solution can serve as a better indicator of the effect of a drooping upper eyelid (ptosis) by covering part of the upper portion of the field of vision as compared to traditional use of tape to lift up the upper eyelid in the evaluation of patients for surgical upper eyelid repair.

NCT ID: NCT05770973 Completed - Ptosis, Eyelid Clinical Trials

Effect of Eyelid Patching After Ptosis Surgery

Start date: July 1, 2020
Phase: N/A
Study type: Interventional

The goal of this randomized, controlled, observer-blinded study is to compare the effect of compression dressing after ptosis surgery. The main question it aims to answer are: Effect of dressing on edema, hematoma, scar formation, ocular surface irritation and postoperative pain. Patients are randomized after surgery for compression dressing or not. Results are scored by a blinded observer. type of study: clinical trial

NCT ID: NCT05750251 Recruiting - Eyelid Diseases Clinical Trials

Effect of Upper Eyelid Surgeries on Corneal Characteristics

Start date: February 6, 2023
Phase:
Study type: Observational [Patient Registry]

The goal of this prospective observational study is to learn about the impact of conventional eyelid correction surgery on the eye's health and function in ptosis and eyelid retraction patient. The main questions it aims to answer are: • 1. Changes in corneal topography, higher-order corneal aberrations, corneal biomechanical characteristics, and corneal epithelial thickness before and after the surgery 2. Influence of corneal refraction examinations , vision change, and tear film function after the surgery Fifty participants will undergo conventional eyelid correction surgery by the same ophthalmologist (YH Wei) and non-invasive examinations before and after the surgery. The patient will be separate to 2 groups, including 30 with correction for ptosis and 20 with correction for eyelid retraction. The research will collect information of the operated eye and fellow eye, and the data will be compared between operated and fellow eye and with the other group.

NCT ID: NCT05715346 Completed - Clinical trials for Acquired Blepharoptosis

LEV102 Topical Gel in Acquired Blepharoptosis

Start date: June 24, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

Phase 1/2a, multicenter, randomized, vehicle-controlled, double-masked, multiple-dose, parallel-group study conducted in adult subjects with acquired blepharoptosis.

NCT ID: NCT05480098 Recruiting - Ptosis, Eyelid Clinical Trials

Brimonidine for Intraoperative Hemostasis

Start date: May 26, 2022
Phase: Phase 4
Study type: Interventional

The purpose of this study is to observe and report the effects of topical ophthalmic brimonidine in oculofacial plastic surgery.