Clinical Trials Logo
  1. Home
  2. Blepharitis
  3. NCT03926026

Study Evaluating the Safety and Tolerability of NCX 4251 for the Treatment of Acute Exacerbations of Blepharitis

Blepharitis Clinical Trial

Official title:
A Multi-Center, Randomized, Double-Masked, Placebo-Controlled, Dose-Escalation, Phase 2 Study Evaluating the Safety and Tolerability of NCX 4251 (Fluticasone Propionate Nanocrystal) Ophthalmic Suspension, 0.1% QD and BID for the Treatment of Acute Exacerbations of Blepharitis

Clinical Trial Summary

This is a multi-center, randomized, double-masked, placebo-controlled, Phase 2 study evaluating the safety and tolerability of NCX 4251 (fluticasone propionate nanocrystal) Ophthalmic Suspension 0.1% QD and BID for the treatment of acute exacerbations of blepharitis. The study will be performed in two sequential dose escalating cohorts. The study is designed to select the dose(s) of NCX 4251 to advance into the next stage of development, and to assess the safety and tolerability of NCX 4251 Ophthalmic Suspension.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03926026
Study type Interventional
Source Nicox Ophthalmics, Inc.
Contact
Status Completed
Phase Phase 2
Start date March 18, 2019
Completion date October 21, 2019
View Details
See also
  Status Clinical Trial Phase
Completed NCT04475432 - Safety and Efficacy of TP-03 for the Treatment of Demodex Blepharitis Phase 2/Phase 3
Completed NCT05062564 - Efficacy of LipiFlow in Patients Affected by Meibomian Gland Dysfunction in Reducing Post-cataract Surgery Dry Eye N/A
Completed NCT05629390 - Trial to Evaluate the Efficacy and Safety of TP-03, LIBRA Study Phase 3
Terminated NCT02938078 - Ocular Comfort and Inflammation in Lid Hygiene Therapy N/A
Completed NCT01408082 - Efficacy and Safety Study of a Steroid/Antibiotic Combination Eyedrop to Treat Non-Bacterial Blepharitis Phase 3
Completed NCT01028027 - Loteprednol and Tobramycin Versus Tobramycin and Dexamethasone, in the Treatment of Blepharokeratoconjunctivitis Phase 3
Recruiting NCT04858113 - Short-term Effects on Tear Film (Baby Shampoo vs Blephasol) N/A
Completed NCT00560703 - Treatment of Patients With Blepharitis and Facial Rosacea Phase 2
Recruiting NCT02455895 - Efficacy of iLid Cleanser (Avenova) Versus Vehicle on Ocular Skin Flora N/A
Completed NCT00894530 - The Effects of Azithromycin Ophthalmic Solution, 1% Versus Placebo in Subjects With Blepharitis During a Four-Week Treatment Period (P08638) Phase 2
Completed NCT01115192 - Blephacura Versus Baby Shampoo to Treat Blepharitis N/A
Completed NCT02386774 - Innovative Imaging of the Conjunctiva, Cornea, and Ocular Adnexa N/A
Completed NCT01808560 - Treatment of Meibomian Gland Dysfunction Prior to Cataract Surgery N/A
Completed NCT01089608 - Efficacy and Safety Assessment of Azyter® Eye Drops (T1225) in Patients With Blepharitis Phase 2
Completed NCT00629941 - Safety and Efficacy Study of AzaSite® in Subjects With Blepharitis Phase 4
Completed NCT00629590 - Safety and Efficacy Pilot Study of AzaSite (Azithromycin) in Subjects With Blepharitis Phase 4
Recruiting NCT04603222 - Evaluation of SUMMIT BRUSH in Treatment of Blepharitis N/A
Completed NCT02218489 - Safety and Efficacy of KPI-121 in Subjects With Inflammatory Meibomian Gland Disease Phase 2
Completed NCT00796926 - Trial to Compare the Efficacy of Systane Ultra and Refresh Drop in the Treatment of Dry Eye in Asian Eyes Phase 3
Completed NCT00803452 - Lipids of the Human Tear Film and Their Effect on Tear Stability Phase 4