Can Blood Panels Provide Early Warning of Bleeding in Patients on ECMO?

Status Withdrawn

Clinical Trial Summary

This is a prospective, observational study of 60 adult patients anticoagulated with bivalirudin for extracorporeal membrane oxygenation (ECMO). The study aims to identify the most precise early warning blood test or panel of blood tests to predict bleeding in patients on bivalirudin/ECMO. The project will involve comparing currently used blood tests with an extended panel of coagulation and metabolic blood tests with the aim of early warning of impending bleeding to allow intervention in the form of adjusted bivalirudin dose, modification of other risk factors, or transfusion with hemostatic products targeted to documented coagulation test abnormalities.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04478136
Study type	Observational
Source	Montefiore Medical Center
Contact
Status	Withdrawn
Phase
Start date	December 1, 2021
Completion date	June 1, 2023

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT04058223` - Comparison of the Short-term Outcomes of Using DST and PPH Staplers in the Treatment of Grade III and IV Hemorrhoids
Completed	`NCT03678168` - A Comparison Between Conventional Throat Packs and Pharyngeal Placement of Tampons in Rhinology Surgeries	N/A
Completed	`NCT05669313` - The Effects of Hypothermia and Acidosis on Coagulation During Treatment With Rivaroxaban Measured With ROTEM
Completed	`NCT04590898` - Peri-device Leakage Closure After LAAO
Active, not recruiting	`NCT05563883` - Atrial Fibrillation and Cancer: a Nationwide French Cohort Study
Not yet recruiting	`NCT04537533` - Tranexamic Acid Infusion in Low Dose Versus in High Dose for Reducing Blood Loss in Radical Cystectomy Operations	Phase 4
Withdrawn	`NCT02851940` - Pain and Bleeding Following Hypertonic Saline Sclerotherapy Compared to Brand Ligation for Symptomatic Hemorrhoids	N/A
Completed	`NCT02722720` - Carotid Arteries Stenting Complications: Transradial Approach Versus Transfemoral	N/A
Recruiting	`NCT02279186` - Effectiveness of Intravenous Tranexamic Acid in Reducing Blood Loss During and After Cesarean Section	Phase 4
Active, not recruiting	`NCT02244853` - Heart Rate and Cardiovascular Diseases Prognosis in People With Stable Coronary Artery Disease	N/A
Completed	`NCT02980497` - Antiplaque/Antigingivitis Efficacy of Essential Oil Mouthrinses in Six-Month Study	N/A
Completed	`NCT02092415` - Assessment of Limb Perfusion During Junctional Tourniquet	N/A
Completed	`NCT02245854` - Efficacy and Safety of a New Polypectomy Snare for Cold-polypectomy for Small Colorectal Polyps	N/A
Not yet recruiting	`NCT01438736` - Is Cerazette Use Before Nexplanon Insertion Predictive for Bleeding Pattern?	Phase 4
Completed	`NCT00515541` - Lovaza's Effect on the Activation of Platelets	Phase 2
Completed	`NCT00143715` - Oral Vitamin K for Warfarin Associated Coagulopathy	Phase 3
Terminated	`NCT03954314` - DEPOSITION - Decreasing Postoperative Blood Loss by Topical vs. Intravenous Tranexamic Acid in Open Cardiac Surgery	Phase 3
Recruiting	`NCT05945680` - Tranexamic Acid in Breast Esthetic Surgery.	Phase 4
Recruiting	`NCT03783182` - Betamethasone (Betapred®) as Premedication for Reducing Postoperative Vomiting and Pain After Tonsillectomy	Phase 4
Not yet recruiting	`NCT05464394` - Peroperative Administration of Tranexamic Acid in Roux-en-Y Gastric Bypass and One-anastomosis Gastric Bypass	Phase 3