Bladder Cancer Clinical Trial
Official title:
Evaluation of the Preoperative Detection of Muscle Invasion in Bladder Cancer With Contrast-enhanced Ultrasonography: A Prospective Study
To evaluate the diagnostic accuracy of CEUS for the preoperative staging of bladder cancer, which would benefit the implementation of efficient therapeutic strategies.
Status | Recruiting |
Enrollment | 163 |
Est. completion date | December 1, 2022 |
Est. primary completion date | September 1, 2021 |
Accepts healthy volunteers | |
Gender | All |
Age group | 18 Years to 75 Years |
Eligibility | Inclusion Criteria: - (a) eligible patients should be 18-year-old or older; - (b) patients should have a histologically or cytologically confirmed diagnosis of primary bladder cancer; - (c) patients should not have had any surgery, chemotherapy, immunotherapy, or any therapy before CEUS diagnosis. Exclusion Criteria: - (a) participants with confirmed to have no carcinoma of the bladder; - (b) participants with previous pelvic surgery, who had undergone therapy, any bladder surgery, or had received chemotherapy, radiotherapy or immunotherapy; - (c) participants diagnosed with tumor recurrence or metastasis; (d) participants who were allergic to ultrasound contrast agents or could not tolerate CEUS examination, for instance, with recent myocardial infarction, angina pectoris, cardiac insufficiency, severe cardiac arrhythmia, a right/left cardiac shunt, severe pulmonary hypertension, uncontrolled systemic hypertension, acute respiratory distress syndrome, or chronic obstructive pulmonary disease. |
Country | Name | City | State |
---|---|---|---|
China | Sun Yat-sen Memorial Hospital, Sun Yat-sen University | Guangzhou | Guangdong |
Lead Sponsor | Collaborator |
---|---|
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University |
China,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Detection of Muscle Invasion in Bladder Cancer | To evaluate the preoperative staging of bladder cancer,whether it is non-muscle invasive bladder cancer (NMIBC) or muscle invasive bladder cancers (MIBC) | within 3 minutes |
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