New Biomarkers of Neurological Outcome After a Sudden Cardiac Death

Status Active, not recruiting

Clinical Trial Summary

The aim of the project is to establish the value of circulating microparticles as a new biomarker for neurological prognosis of patients recovered from sudden cardiac death who remain comatose.

Clinical Trial Description

This is a pilot study. Analytical, observational, longitudinal, retrospective and prospective, non-randomized. Patients recovered from sudden cardiac death of ischemic cause and remain comatose will be included in the protocol if they fit the pre-specified inclusion criteria. Biological samples will be collected (at admission, at 24 and 72 hours) and stored in the Biobank of Hospital de la Santa Creu i Sant Pau for further analysis. In addition demographic, clinical and analytical variables will be collected. At the end of the recruitment period, we will analyse the concentrations of circulating microparticles according to ICCC-IIBSantPau methodology in the samples obtained. The primary outcome variable will be the neurological status at Coronary Care Unit discharge and at 6 months. The objective of the study will evaluate the relationship between the neurological status and the blood concentrations of circulating microparticles. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03962361
Study type	Observational
Source	Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Contact
Status	Active, not recruiting
Phase
Start date	February 2016
Completion date	December 2019

View Details

See also
Status	Clinical Trial	Phase
Active, not recruiting	`NCT05095324` - The Biomarker Prediction Model of Septic Risk in Infected Patients
Recruiting	`NCT05548933` - Effects of Non-surgical Periodontal Therapy on Severe Periodontitis and Hyperlipidemia
Active, not recruiting	`NCT03926572` - Acute Decompensation of Pulmonary Hypertension	N/A
Recruiting	`NCT05372159` - Vanderbilt Memory and Aging Project
Completed	`NCT03173586` - Sugar Sweetened Beverage Intake and Biomarkers of Cardiometabolic Risk in US Women	N/A
Completed	`NCT04554628` - Early Prediction of Acute Kidney Injury Among Patients Admitted to Surgical ICU	N/A
Terminated	`NCT03250312` - The Effects of OMT on the Expression Patterns of Immune Cell Biomarkers	N/A
Recruiting	`NCT04666766` - Detecting Traumatic Intracranial Hemorrhage With Microwaves and Biomarkers	N/A
Completed	`NCT04573543` - The Role of Immune Semaphorins in NAFLD
Completed	`NCT03193671` - Evaluation and Implementation of New Biomarkers and Algorithms for Diagnosis of Ovarian Cysts/Tumors in the Pelvis	N/A
Recruiting	`NCT06047132` - PREDICTIVE ABILITY OF A PANEL OF BIOMARKERS IN SALIVA IN HEALTHY AND PERIODONTALLY AFFECTED SUBJECTS
Completed	`NCT05361460` - Patients Experiences of Early Postoperative Cognition
Recruiting	`NCT05706194` - Early Neuroprognostication After OHCA
Recruiting	`NCT05138731` - Metabolomics Profiling of Coronary Heart Disease
Recruiting	`NCT06446895` - Biomarkers of Inflammation and Endothelial Dysfunction in Patients With Myocardial Infarction With Non-obstructive Coronary Arteries
Not yet recruiting	`NCT04563000` - Impact of Vitamin C on Biomarkers of Neurologic Injury in Survivors of Cardiac Arrest	Phase 2
Completed	`NCT05138692` - Biomarkers and Outcome 1 and 10-15 Years After Severe Traumatic Brain Injury
Completed	`NCT02247999` - Improving Cervical Cancer Screening Among HIV-Infected Women in India
Active, not recruiting	`NCT02732301` - Postoperative Gastrointestinal Dysfunction After Cardiac Surgery - Occurrence and Search for Biomarkers
Not yet recruiting	`NCT03269019` - Thrombotic Biomarkers to Predict Thrombosis in Heparin-induced Thrombocytopenia	N/A