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Interventions Meant to Improve the Outcome of Critical Care Patients in the ED

Biomarker Clinical Trial

Official title:
A Bundle of Interventions Meant to Improve the Outcome of Critical Care Patients in the Emergency Department

Clinical Trial Summary

This study aims to identify the prognostic role of procalcitonin (PCT), soluble Triggering Receptor Expressed on Myeloid Cells-1 (sTREM-1), the soluble form of the urokinase plasminogen activator receptor (suPAR), highly sensitive C-reactive protein (hs-CRP), Interleukin-6 (IL-6), and azurocidin 1 (AZU1) in 28-day mortality for patients with sepsis in Emergency Department.

Clinical Trial Description

The levels of the specified biomarkers were measured upon patient arrival at the Emergency Department (ED) and analyzed their correlation with 28-day mortality. The values of these biomarkers were monitored over the initial three days following admission to the ED, aiming to explore their potential in guiding the de-escalation of antibiotic treatment. Considering their prognostic significance, the main goal is to develop a novel scoring system tailored for use in the emergency department setting. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06338111
Study type Observational
Source Iuliu Hatieganu University of Medicine and Pharmacy
Contact
Status Completed
Phase
Start date November 9, 2020
Completion date April 30, 2023
View Details
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