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NCT02867488 Clinical Trial

Dose-response Effects of Soybean Oil in Salad Dressing on Carotenoid/Fat-soluble Vitamin Bioavailability in Salad Vegetables

Biological Availability Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT02867488
Other study ID # 08-549
Secondary ID
Status Completed
Phase N/A
First received August 11, 2016
Last updated August 16, 2016
Start date April 2009
Est. completion date June 2016

Study information
Verified date August 2016
Source Iowa State University
Contact n/a
Is FDA regulated No
Health authority United States: Institutional Review Board
Study type Interventional

Clinical Trial Summary

The objectives will be to evaluate the dose-response between the amount of soybean oil in salad dressing and the absorption of: 1) carotenoids, phylloquinone, and tocopherols in salad vegetables; 2) retinyl palmitate formed from the provitamin A carotenoids, alpha- and beta-carotene.

Recruitment information / eligibility
Status Completed
Enrollment 0
Est. completion date June 2016
Est. primary completion date November 2009
Accepts healthy volunteers No
Gender Female
Age group 18 Years to 40 Years
Eligibility Inclusion Criteria:

- General good health as determined by interview, blood biochemistry profile, complete blood count, and plasma lipid and lipoprotein profile

Exclusion Criteria:

- Cigarette smoking, frequent alcohol consumption

- Use of vitamin/mineral supplements

- Lactose intolerance

- Known food allergies

- Body mass index (BMI) 30 or higher

- Eating disorder or restrained eating

- Vegetarianism

- Hyperlipidemia

- Current or planned pregnancy

- Use of hormonal contraceptives (affects chylomicron clearance); use of plant sterols or medications known to affect lipid metabolism

Study Design

Endpoint Classification: Bio-availability Study

Related Conditions & MeSH terms

Intervention

Other:
• Soybean oil in salad dressing

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Iowa State University

Outcome
Type Measure Description Time frame Safety issue
Primary Area under the curve for carotenoids, phylloquinone, tocopherols, and retinyl palmitate in the plasma chylomicron fraction 0-9.5 hours postprandially No
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