Food and the Brain

Binge Eating Clinical Trial

Official title:

Emotion and Reward Processing in Binge Eating

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02743000
• Other study ID #: 35204
• Status: Completed
• Start date: January 2016
• Est. completion date: April 2020

Study information

• Verified date: October 2020
• Source: Stanford University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The proposed study will examine the role of reward and emotion in women with and without a history of binge eating. It is important to understand how the brain responds to reward and emotion in binge eating in order to identify different pathways toward binge eating and provide individualized targets for treatment. This is particularly important in light of the fact that for many patients, the current treatments for binge eating are not effective.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 83
• Est. completion date: April 2020
• Est. primary completion date: April 2020
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 18 Years to 35 Years

Eligibility

Inclusion Criteria:

• Female

• Ages 18-35

• with or without current binge eating behaviors

Exclusion Criteria:

• Any contraindication for MRI (orthodontia, vascular stents, metallic ear tubes, metal implants, piercings, etc).

• substance abuse

• traumatic brain injury

• BMI < 18.5

• pregnant women

Related Conditions & MeSH terms

• Binge Eating
• Binge-Eating Disorder
• Bulimia

Locations

Country	Name	City	State
United States	Stanford University, Department of Psychiatry	Stanford	California

Sponsors (1)

Lead Sponsor	Collaborator
Stanford University

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Brain activity during rest	Functional magnetic resonance imaging will be used to measure brain activity at rest and connectivity between brain regions will be examined.	Baseline
Primary	Brain activity during emotion conflict	Functional magnetic resonance imaging will be used to measure brain activity during a task where participants respond to images of faces with emotional expressions overlaid with an emotion word written in text. We will focus on brain response during this task when emotion face vs word are in conflict.	Baseline
Primary	Brain activity during monetary wins and losses	Functional magnetic resonance imaging will be used to measure brain activity during a game where participants can win or lose money if they respond to a shape on the computer screen. Brain response during wins and losses will be examined.	Baseline