Binge-Eating Disorder Clinical Trial
Official title:
An Investigation of Appetitive Cognitive Control: Impact on Treat Outcomes for Binge Eating
The primary aim of this study is to determine how inhibitory neurobiological and neurocognitive processes relate to binge eating treatment outcome.
Binge eating disorder (BED) is characterized by reoccurring binge eating episodes that
consist of eating a subjectively or objectively large amount of food over a period of time
accompanied by a sense of loss control over eating, in the absence of recurrent compensatory
behaviors (e.g., purging). Cognitive behavioral therapy (CBT) is the current gold-standard
treatment for reducing binge eating episodes in BED patients. The first-line of recommended
CBT treatment is a self-guided intervention called CBT-Guided Self-Help (CBT-GSH). However,
for a substantial minority of patients, CBT-GSH fails to reduce binge episodes after
treatment. Preliminary findings of the literature suggests that individuals with BED possess
deficits in inhibitory control as it relates to food-stimuli. We are studying how inhibitory
neurobiological and neurocognitive processes relate to binge eating treatment outcome.
This study involves a brief phone screen and research assessment (approximately 5 hours) to
determine eligibility. Eligible participants will receive CBT-GSH, which will include a
one-hour clinical intake followed by 6 therapy sessions (approximately 30 minutes each).
Participants will also complete research assessments at mid-treatment, post-treatment, and 3
month follow-up intervals. Research assessments include a battery of questionnaires,
computerized tasks, interviews, and a task using functional Near Infrared Spectroscopy (fNIR)
imaging.
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