FDA Approved Medication to Reduce Binge Eating and/or Purging

Status Completed

Clinical Trial Summary

This study will demonstrate the efficacy of Qsymia versus placebo in treating bulimia nervosa and binge eating disorder.

Clinical Trial Description

Bulimia nervosa (BN) and binge eating disorder (BED) are serious mental disorders associated with adverse psychological and physical consequences. Treatment options to date offer limited success, leaving at least 50-70% of patients still symptomatic after treatment. The purpose of the study is to evaluate whether phentermine-topiramate (Qsymia), a medication currently FDA approved for the treatment of obesity, will demonstrate efficacy—compared to placebo- when re-purposed for patients with bulimia and binge eating.

Participants will be randomized into one of two conditions: qsymia or Placebo. One condition will receive 3 months of phentermine-topiramate, a 2 week washout, then 3 months of placebo. The other condition will receive 3 months of Placebo, a 2 week washout, then 3 months of phentermine-topiramate. Participants will receive a total of 6 months of treatment and then have a 2 month follow-up off of medications. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02553824
Study type	Interventional
Source	Stanford University
Contact
Status	Completed
Phase	Phase 1
Start date	October 30, 2015
Completion date	April 15, 2017

View Details

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