Risk Factors Associated With Binge Drinking Behaviors Among College Students

Binge Drinking Clinical Trial

— AlcoolPredict  

Official title:

AlcoholPredict: Neuropsychology, Brain Imaging and Genetic Polymorphisms in Binge Drinking

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02794311
• Other study ID #: PO13129
• Status: Completed
• Phase: N/A
• Start date: February 2015
• Est. completion date: September 24, 2019

Study information

• Verified date: June 2020
• Source: CHU de Reims
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to specify the psychological, cognitive, neuro-functional and genetic profile associated with binge drinker behaviors among young adults. Results will help identifying more precisely vulnerability factors associated with this pattern of alcohol consumption and guiding prevention efforts.

Description:

Binge drinking behavior is characterised by speed of drinking on a particular occasion, frequency of drunkenness during the most recent six month period, and the percentage of times getting drunk when drinking. The prevalence of weekly binge drinking among European Union drinkers in 2009 was reported to be 28% of the student population, and 33% among all young people aged 15-24. The consequences of this behavior are multiple and often dramatic, they include: academic failure, violent acts, rape, domestic or road accidents. The study aims to identify vulnerability factors associated with binge drinking. The protocol explores the psychological (personality), neuropsychological (executive functions, memory), genetic (snp polymorphisms) and neuro-anatomical (fMRI) patterns associated with binge drinking behavior.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 125
• Est. completion date: September 24, 2019
• Est. primary completion date: September 24, 2019
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 25 Years

Eligibility

Inclusion criteria :

• Males or females

• Right-handed

• Aged 18-25 years

• Native French speaker, able to read French and complete study evaluations

• Caucasian

• Able to provide informed written and verbal consent

Exclusion criteria

• A significant general medical illness, including neurological disorders, mental retardation or head trauma

• Depression, bipolar disorder, schizophrenia or schizoaffective disorder diagnostic according to DSM-IV

• Handling of psychotropics substances

• A sensorial impairment (visual and/or hearing)

• Women who are pregnant

• Contraindication to the use of MRI (pacemaker, metal in their body)

Related Conditions & MeSH terms

• Binge Drinking

Intervention

Other:
• Alcoolpredict
psychological (personality), neuropsychological (executive functions, memory), genetic (snp polymorphisms) and neuro-anatomical (fMRI)

Locations

Country	Name	City	State
France	Chu Reims	Reims

Sponsors (1)

Lead Sponsor	Collaborator
CHU de Reims

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Neuropsychological test : Mini International Neuropsychiatric Interview (M.I.N.I)		day 1
Primary	Neuropsychological test : Wisconsin Card Sorting Test (WCST)		V2(3 weeks later)
Primary	Genetics tests (Single Nucleotide Polymorphism)		V2(3 weeks later)
Primary	MRI - signal BOLD (" Blood Oxygen Level Dependant ").		V3(up to 2 month)
Primary	Neuropsychological test : Family Informant Schedule and Criteria (FISC)		day 1
Primary	Neuropsychological test : Alcohol Use Questionnaire		day 1
Primary	Neuropsychological test :Trail Making Test, partie A et B		V3(up to 2 month)
Primary	Neuropsychological test : Plus/Minus Test		V3(up to 2 month)
Primary	Neuropsychological test :Go/No-Go		V3(up to 2 month)