Clinical Trials Logo
  1. Home
  2. Biliary Stricture
  3. NCT01148199

Self-expandable Metallic Stent Versus Multiple Plastic Stents in Post Orthotopic Liver Transplantation Biliary Stenosis

Biliary Stricture Clinical Trial

Official title:
Self-expandable Metalic Stent Versus Multiple Plastic Stents in Post OLT Biliary Stenosis: Prospective, Randomized, Controlled Trial.

Clinical Trial Summary

Biliary complications are one of the most common problems after orthotopic liver transplantation (OLT),occurring in up to 24% of patients.

Anastomotic strictures have been endoscopically managed with plastic stents placement. Recently, partially and fully covered metal stents have been alternatively used to treat refractory benign biliary stenosis. The investigators purpose is to compare efficacy and safety of metallic stents versus multiple plastic stents in the endoscopic management of post transplant biliary complications.

Clinical Trial Description

Patients with biliary stricture after OLT will be randomly assigned following simple randomization to temporary placement of fully covered self-expandable metal stent (SEMS) or multiple plastic stents placement were randomized according to a computer generated randomization sequence and allocated in a 1:1 ratio to one of two treatment groups.

Final success will be defined as clinical resolution of the stricture without the need to repeat endoscopic, percutaneous or surgical treatment. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01148199
Study type Interventional
Source Hospital Israelita Albert Einstein
Contact
Status Completed
Phase Phase 2/Phase 3
Start date August 2009
Completion date February 2016
View Details
See also
  Status Clinical Trial Phase
Completed NCT03115411 - Prospective Evaluation of Winged Biliary Stent Patency in Patients With Benign Biliary Obstruction N/A
Completed NCT02041390 - Effect of Short Message Service Intervention on Stent Removal/Exchange Adherence in Patients With Benign Pancreaticobiliary Diseases N/A
Recruiting NCT01439698 - Radio Frequency Ablation in the Management of Pancreatico-biliary Disorders: A Multicenter Registry N/A
Terminated NCT01413386 - Efficacy and Safety of the Paclitaxel Eluting Covered Biliary Stent to the Common Covered Metallic Biliary Stent N/A
Completed NCT01543256 - WallFlex Biliary Fully Covered (FC) Chronic Pancreatitis Study N/A
Enrolling by invitation NCT04572711 - Prospective Evaluation of Biliary Tissue Sampling With ERCP
Recruiting NCT03229655 - Evaluation of Sequential Stent Addition vs. Incremental Dilation & Stent Exchange for Management of Anastomotic Biliary Strictures After Liver Transplantation N/A
Completed NCT02916199 - Primary Needle Knife Fistulotomy Versus Conventional Cannulation Method N/A
Recruiting NCT01522573 - T-EUS for Gastrointestinal Disorders: A Multicenter Registry N/A
Recruiting NCT01524146 - Photodynamic Therapy (PDT) Cholangiocarcinoma Registry N/A
Completed NCT02281019 - SpyGlass AMEA Registry
Recruiting NCT04010734 - Primary Cholangioscopy Versus ERCP in the Diagnosis of Biliary Strictures N/A
Not yet recruiting NCT06369896 - Digital Single-operator Cholangioscopy and Intraductal Ultrasound for Nonicteric Biliary Strictures
Recruiting NCT04391153 - FISH in Diagnosis of Biliary Stricture N/A
Active, not recruiting NCT03997994 - DIGEST I Drug Coated Balloon for Biliary Stricture N/A
Enrolling by invitation NCT03951324 - Volumetric Laser Endomicroscopy's (VLE) Diagnostic Accuracy Validation Study: Impact on Clinical Management Study
Unknown status NCT01085747 - Endoscopic Treatment of Biliary Stricture Caused by Chronic Pancreatitis N/A
Completed NCT02105181 - Fully Covered Self-expandable Metal Stents (FCMS) in Benign Biliary Strictures N/A
Recruiting NCT05761483 - Endoscopic Management of Non-anastomotic Biliary Strictures Following Liver Transplantation.
Completed NCT03673033 - Biliary Complications in Live Donor Liver Transplantation