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Biliary Stricture clinical trials

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NCT ID: NCT01524146 Recruiting - Biliary Stricture Clinical Trials

Photodynamic Therapy (PDT) Cholangiocarcinoma Registry

PDTRegistry
Start date: November 2011
Phase: N/A
Study type: Observational

Currently, very few centers offer Photodynamic therapy for unresectable Cholangiocarcinoma in the United States. Several European studies have reported the efficacy and safety of Photodynamic Therapy (PDT) for Cholangiocarcinoma, however, only a few studies have reported the same in the United States. The establishment of a registry to capture all PDT cases within and outside US can help the investigators evaluate a larger and non-ambiguous sample population. This would help the investigators evaluate the technical success rates, clinical success rates, feasibility and safety of PDT for unresectable cholangiocarcinoma. With more endoscopists considering PDT as a therapeutic option along with adjuvant treatment for cholangiocarcinoma, there is a need to further evaluate the efficacy and safety of such combined procedures as well. The ultimate objective is to assess if PDT with or without additional or adjuvant treatment options prolongs survival duration and improves quality of life in patients with unresectable cholangiocarcinoma. This multicenter registry has been initiated: - To document the impact of PDT on the clinical management of unresectable cholangiocarcinoma. - To assess the clinical and technical success rates of PDT for unresectable cholangiocarcinoma.

NCT ID: NCT01522573 Recruiting - Pancreatic Cancer Clinical Trials

T-EUS for Gastrointestinal Disorders: A Multicenter Registry

EUSERCPReg
Start date: November 2011
Phase: N/A
Study type: Observational

The purpose of this registry is to record information and evaluate the impact of Endoscopic Ultrasound (EUS) Guided Endoscopic retrograde cholangiopancreatography (ERCP) on the management of pancreatico-biliary disorders. The registry will evaluate efficacy, safety and technical success of the Endoscopic Ultrasound (EUS)Guided Endoscopic retrograde cholangiopancreatography (ERCP) procedures. The safety and efficacy of various EUS-Guided ERCP procedures have been assessed in a series of studies. This multi-center registry has been initiated: - To document the impact of EUS-Guided ERCP procedures on the management of pancreatico-biliary disorders including malignancies. - To assess the clinical and technical success rates of EUS-Guided ERCPs for diagnostic or therapeutic procedures. Design is retrospective and prospective registry study. Procedures that will be captured include: 1. EUS-Coils placement 2. EUS Glue injection 3. EUS-Fiducial placement 4. EUS-Neurolysis 5. EUS-Stent placement 6. EUS-alcohol injection 7. EUS-fluid collection, abscess or cavity drainage 8. EUS guided ductal drainage 9. EUS-guided Ablation 10. EUS-guided anastomosis 11. EUS Guided ERCP for gallbladder, pancreatic duct or biliary duct drainage

NCT ID: NCT01512563 Completed - Biliary Stricture Clinical Trials

Patency and Safety of the Drug Eluting Covered Biliary Stent Comparing to the Common Covered Biliary Stent

MIRA-cover
Start date: February 2007
Phase: N/A
Study type: Interventional

Paclitaxel covered metal biliary stent extents their patency rate comparing to the Common Covered Metallic Biliary Stent.

NCT ID: NCT01439698 Recruiting - Pancreatic Cancer Clinical Trials

Radio Frequency Ablation in the Management of Pancreatico-biliary Disorders: A Multicenter Registry

RFA-Registry
Start date: September 2011
Phase: N/A
Study type: Observational [Patient Registry]

The objective of this protocol is to establish a multicenter registry to evaluate the impact of radiofrequency ablation in the management of patients with pancreatico-biliary disorders including malignancies.

NCT ID: NCT01439620 Completed - Biliary Stricture Clinical Trials

Optical Frequency Domain Imaging (OFDI) for Biliary Stricture Imaging

Start date: February 2009
Phase: N/A
Study type: Interventional

The goal of this study is to evaluate the potential of comprehensive biliary Optical Frequency Domain Imaging (OFDI) for assessing common bile duct or common hepatic duct strictures, determining cholangiocarcinoma margins, and evaluating primary sclerosing cholangitis (PSC).

NCT ID: NCT01413386 Terminated - Biliary Stricture Clinical Trials

Efficacy and Safety of the Paclitaxel Eluting Covered Biliary Stent to the Common Covered Metallic Biliary Stent

MIRAII
Start date: September 2011
Phase: N/A
Study type: Interventional

Paclitaxel covered metal biliary stent is non-inferior to common covered metal biliary stent in their patency rate and safety at the 6 months after stenting.

NCT ID: NCT01148199 Completed - Biliary Stricture Clinical Trials

Self-expandable Metallic Stent Versus Multiple Plastic Stents in Post Orthotopic Liver Transplantation Biliary Stenosis

Start date: August 2009
Phase: Phase 2/Phase 3
Study type: Interventional

Biliary complications are one of the most common problems after orthotopic liver transplantation (OLT),occurring in up to 24% of patients. Anastomotic strictures have been endoscopically managed with plastic stents placement. Recently, partially and fully covered metal stents have been alternatively used to treat refractory benign biliary stenosis. The investigators purpose is to compare efficacy and safety of metallic stents versus multiple plastic stents in the endoscopic management of post transplant biliary complications.

NCT ID: NCT01085747 Unknown status - Clinical trials for Chronic Pancreatitis

Endoscopic Treatment of Biliary Stricture Caused by Chronic Pancreatitis

Start date: March 2008
Phase: N/A
Study type: Observational

Benign biliary strictures can be endoscopically treated with plastic or self-expandable metal stents (SEMS). The purpose of the prospective randomized study is to compare the safety and feasibility of covered SEMS with multiple plastic stents in the treatment of benign biliary stricture caused by chronic pancreatitis.

NCT ID: NCT01014390 Completed - Biliary Stricture Clinical Trials

WallFlex Biliary Fully Covered (FC) Benign Stricture Study

Start date: December 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety and performance of the WallFlex® Biliary RX Fully Covered Stent as a treatment of biliary obstruction resulting from benign bile duct strictures.

NCT ID: NCT00894348 Completed - Biliary Stricture Clinical Trials

Factors Predicting Positive Yields on Biliary Brush Cytology During Endoscopic Retrograde Cholangiopancreatography

ERCP
Start date: January 2009
Phase: N/A
Study type: Observational

To determine factors associated with a positive yield of malignancy on biliary brush cytology obtained by ERCP.