Efficacy of Intraductal Radiofrequency Ablation in Combination With

Status Completed

Clinical Trial Summary

The study aim to evaluate the efficacy of intraductal radiofrequency ablation for unresetable hilar cholangiocarcinoma in addition to biliary stenting. The patient would be randomized into 1:1 ratio of conventional group who received biliary stenting alone, and RFA group who receive intraductal RFA before biliary stenting. Immediate complications as well as long term stent patency and patient survival would be studied.

Clinical Trial Description

Study design: randomized single-blind control trial Study population: patient with unresectable hilar cholangiocarcinoma with obstructive jaundice who need hilar biliary stenting Primary endpoint: Biliary stent patency time Secondary endpoint: Patient survival Intervention 1. Recruited patients randomly assigned into 2 groups, conventional and RFA group by sealed enveloped 2. All patients receive endoscopic biliary stenting. Those in RFA group receive RFA before biliary stent. 3. Monitor for adverse event during hospitalization and during follow up 4. Follow up as outpatient in 4-weekly interval with monitoring of serum liver function test as routine ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04611100
Study type	Interventional
Source	Rajavithi Hospital
Contact
Status	Completed
Phase	N/A
Start date	April 1, 2020
Completion date	December 30, 2021

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT03118973` - Evaluation of Efficacy and Safety of Goff Transpancreatic Septotomy vs. Double Wire Technique for Achieving Biliary Access in Technically Challenging ERCPs	N/A
Recruiting	`NCT05429203` - Comparison of Duodenoscope With Single-use Distal Cover and the Conventional Reusable Duodenoscope	N/A
Completed	`NCT03002051` - EUS-guided Transenteric Drainage With a Novel Lumen-apposing Metal Stent	N/A
Terminated	`NCT00990366` - Treatment of Biliary Obstruction Using Biliary Stent With or Without Antireflux Valve	N/A
Recruiting	`NCT04929821` - UNITY-B A Prospective, Multicentric, Single-arm Study to Evaluate the Safety and Efficacy of the UNITY-B Biodegradable Balloon-Expandable Biliary Stent System in Subjects With Biliary Strictures	N/A
Completed	`NCT03074201` - Prospective Evaluation of the Ability of Spyglass Cholangioscopy to Facilitate Radiation Free ERCP	N/A
Recruiting	`NCT01524146` - Photodynamic Therapy (PDT) Cholangiocarcinoma Registry	N/A
Recruiting	`NCT01522573` - T-EUS for Gastrointestinal Disorders: A Multicenter Registry	N/A
Completed	`NCT04595058` - LAMS Choledochoduodenostomies: With or Without Coaxial Plastic Stent	N/A
Completed	`NCT03962478` - Combined Stent Insertion and HIFU Ablation for Pancreatic Carcinoma With Biliary Obstruction	N/A
Completed	`NCT02460432` - Comparison of Drug Eluting Stent and Covered Metal Stent in Malignant Biliary Obstruction (MIRA III)	N/A
Active, not recruiting	`NCT03997994` - DIGEST I Drug Coated Balloon for Biliary Stricture	N/A
Completed	`NCT03870386` - EUS Biliary Drainage vs. ERCP	N/A
Not yet recruiting	`NCT06287112` - Prevention of Acute Cholecystitis With ETGBD	N/A
Completed	`NCT03925766` - Laparoscopy-Assisted Transgastric ERCP
Recruiting	`NCT00731419` - Randomised Trial Comparing Metal and Plastic Biliary Stents Stents for Palliating Malignant Jaundice	Phase 4
Not yet recruiting	`NCT05432661` - clınıcal Effects of High-flow Nasal Oxygen Use ın gerıatrıc patıents
Recruiting	`NCT06047990` - Endobiliary Percutaneous Cryobiopsy in Malignant Biliary Obstruction	N/A
Recruiting	`NCT04857424` - Quality of Life Assessment Between Internal Endoscopic Versus Percutaneous Drainage in Biliary Obstruction
Completed	`NCT04319302` - Isolated Vascularized Gastric Tube Biliary Enteric Drainage: A Paediatric Case Series Experience.

Efficacy of Intraductal Radiofrequency Ablation in Combination With Metallic Biliary Stenting in Advanced Hilar Cholangiocarcinoma

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms