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Preoperative Biliary Drainage in Patients With Operable Malignant Periampulary Tumors

Biliary Obstruction Clinical Trial

Official title:
"Impact of Preoperative Biliary Drainage on Surgical and Oncologic Outcomes After Pancreatico-Duodenectomy in Patients With Operable Malignant Periampulary Tumors. A Randomized Controlled Study"

Clinical Trial Summary

The impact of preoperative biliary drainage (PBD) on morbidity and mortality associated with Pancreaticoduodenectomy (PD) in patients with peri-ampulary tumors is still controversial. The objective of this study is to evaluate the impact of PBD on surgical and oncologic outcomes after PD in jaundiced patients with operable peri-ampulary tumors.

Clinical Trial Description

150 consecutive jaundiced patients with suspected operable peri-ampullary tumors were randomized via concealed envelopes into 2 groups (each included 75 patients), group I managed by direct surgery while group II managed by PBD followed by surgery. Both groups were compared regarding perioperative mortality, morbidities, tumor recurrence and 2 years survival rates. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04289831
Study type Interventional
Source University of Alexandria
Contact
Status Completed
Phase N/A
Start date August 2015
Completion date October 2019
View Details
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