Clinical Trials Logo

Clinical Trial Summary

Comparing the effect of Liraglutide on bile acid malabsorption, with colesevelam


Clinical Trial Description

The overall objective of the present study is to provide proof of concept that treatment with the GLP-1 receptor agonist liraglutide is efficacious (as assessed by symptom relief, i.e. response to treatment) and safe (as assessed by adverse effects) in the management of BAM and that it improves bile acid reabsorption (as assessed by SeHCAT) in these patients. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03955575
Study type Interventional
Source University Hospital, Gentofte, Copenhagen
Contact
Status Completed
Phase Phase 4
Start date March 7, 2019
Completion date May 31, 2022

See also
  Status Clinical Trial Phase
Completed NCT03876717 - Effect of the Sequestrant Colesevelam in Bile Acid Diarrhoea Phase 4
Terminated NCT01203254 - Colesevelam for the Treatment of Bile Acid Malabsorption in Patients With Crohn's Disease Phase 4
Completed NCT02628626 - A Study of Colesevelam in Fecal Incontinence Phase 3
Completed NCT02078856 - Double-blind, Randomised Study of A3384 in BAM/BAD Phase 2
Completed NCT03059537 - Validation of Stimulated ∆FGF19 for Diagnosing Bile Acid Diarrhoea Phase 4
Completed NCT03168555 - Changes in Bile Acid Homeostasis and Stool Habits After Cholecystectomy Phase 4
Recruiting NCT05245357 - Impact of Foods on Bile Acids, Metabolites, and Inflammation N/A
Completed NCT03270085 - Trial to Understand Efficacy of Colesevelam in Diarrhea Predominant IBS Patients With Bile Acid Malabsorption Phase 2
Completed NCT05130047 - Aldafermin (NGM282) for Chronic Diarrhea Due to Bile Acid Malabsorption (BAM) Phase 2