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Clinical Trial Summary

Thalassemics can develop liver fibrosis because of iron overload and hepatitis C infection. The latter is the main risk factor for liver fibrosis in transfusion dependent thalassemics. Excess liver iron is clearly recognized as a co factor for the development of advanced fibrosis in patients with hepatitis virus C infection. Hyaluronic acid serum levels correlate with histological stages of liver fibrosis in hepatitis C patients, so it has a good diagnostic accuracy as a non invasive assessment of fibrosis and cirrhosis.there is evidence that suggests Spirulina may help to protect against liver damage, cirrhosis and liver failure in those with chronic liver disease.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT02744547
Study type Interventional
Source Tanta University
Contact
Status Completed
Phase N/A
Start date December 2015
Completion date December 2017

See also
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Completed NCT04092205 - Phase 2a Pilot Study of NBMI Treatment in Patients With Beta Thalassemia Major, Requiring Iron Chelation Phase 2
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Withdrawn NCT04776850 - Pre-transplant Immunosuppression and Donor Stem Cell Transplant for the Treatment of Severe Hemoglobinopathies Early Phase 1
Completed NCT02744105 - Effect of Spirulina on Liver Fibrosis by Transient Elastography in Beta Thalassemic Children With Hepatitis C N/A
Active, not recruiting NCT03101423 - Monitoring of Chimerism After Transplantation in Patients With β Thalassemia Major and the Treatment Strategies for the Reduction of Chimerism N/A
Completed NCT02671695 - Effect of Spirulina Compared to Amlodipine on Cardiac Iron Overload in Children With Beta Thalassemia N/A
Completed NCT00658385 - Assess the Feasibility and Safety of Granulocyte Colony Stimulating Factor (GCSF) Mobilization of CD34+ Hematopoietic Progenitor Cells in Patients With Betathalassemia Major N/A