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Benign Prostatic Hyperplasia clinical trials

View clinical trials related to Benign Prostatic Hyperplasia.

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NCT ID: NCT01757769 Completed - Clinical trials for Benign Prostatic Hyperplasia

Effectiveness and Safety of Silodosin in the Treatment of Benign Prostatic Hyperplasia

SiRE
Start date: May 2011
Phase: Phase 4
Study type: Interventional

The purpose of this study is to confirm in a larger population in Europe the effectiveness and safety observed with silodosin in previous clinical trials.

NCT ID: NCT01716104 Completed - Clinical trials for Benign Prostatic Hyperplasia

Clinical Trial of Safety and Efficacy of Afalaza in Patients With Symptoms of Benign Prostatic Hyperplasia and Risk of Progression

Start date: November 2012
Phase: Phase 3
Study type: Interventional

The purpose of this study is: - To assess safety of Afalaza drug within 12 months in patients with symptoms of benign prostatic hyperplasia (BPH) and risk of progression. - To assess efficacy of Afalaza drug within 12 months in patients with symptoms of benign prostatic hyperplasia and risk of progression.

NCT ID: NCT01678313 Completed - Clinical trials for Benign Prostatic Hyperplasia

Cyclooxygenase-2 (COX-2) Inhibitor Reduces Serum Prostatic Specific Antigen (PSA) Levels

Start date: August 2012
Phase: Phase 2
Study type: Interventional

To investigate the therapeutic effect and safety of celecoxib adding on doxazosin and the potential predictive value of the absence of prostate cancer in the treatment of patients with LUTS/BPH and an elevated serum PSA level. Patients who meet all eligible requirements for entry into the study will be randomized into one of the two treatment groups for 3 months in 2:1 ratio as shown below: 1. Doxazosin 4 mg daily plus celecoxib 200 mg every day (QD) 2. Doxazosin 4mg every day (QD)

NCT ID: NCT01604148 Completed - Clinical trials for Benign Prostatic Hyperplasia

Retrospective Review a Comprehensive Case Database of HoLEP Procedure Performed by a Single Surgeon

Start date: July 2011
Phase: N/A
Study type: Observational

Persistent detrusor overactivity (DO) after transurethral prostatectomy results in symptomatic failure in more than one third of the patients. Storage symptoms are major complaints in the early postoperative period after Holmium Laser Enucleation of the Prostate (HoLEP). To investigate the effect of DO in the patients with Benign Prostatic Obstruction (BPO), the investigators evaluated the changes in the storage symptoms following HoLEP in conjunction with the prescription of the anticholinergic drugs.

NCT ID: NCT01589263 Completed - Clinical trials for Benign Prostatic Hyperplasia

Effectiveness of onaBoNT-A vs Oral Tamsulosin in Men With BPH and LUTS

Start date: June 1, 2012
Phase: Phase 2
Study type: Interventional

Benign prostatic hyperplasia (BPH) and its related symptoms are a common condition that affects nearly half of men over age 50 and 90% of men over 80. Lower urinary tract symptoms (LUTS) caused by BPH can be very troublesome, affect an individual's quality of life significantly, and are costly. his Phase 2 clinical research trial is a double-blind, randomized, placebo-controlled, parallel-group study to compare the treatment effects of onaBoNT-A 200 U versus 0.4 mg per day of oral tamsulosin in male Veterans diagnosed with moderate to severe LUTS [American Urologic Association Symptom Score (AUASS) equal to or greater than 8] associated with BPH. A total of 74 volunteers will be recruited to participate in this clinical trial. Volunteers will include only males who are greater than 50 years of age and diagnosed with LUTS associated with BPH. They are Veterans who visit the Michael E. DeBakey Veterans Affairs Medical Center - Houston (MEDVAMC). There are no eligibility restrictions as to race or ethnicity.

NCT ID: NCT01534793 Completed - Clinical trials for Benign Prostatic Hyperplasia

QUAPELLA (QUAlity of Prostate Enucleation by LUMENIS - Laser)

QUAPELLA
Start date: February 2012
Phase: N/A
Study type: Observational

This observational study aims at describing the learning curve of the Holmium Enucleation of the Prostate (HoLEP) technique using a LUMENIS laser device by senior attending urologists.

NCT ID: NCT01533038 Completed - Clinical trials for Benign Prostatic Hyperplasia

BPH-6: Comparison of the UroLift System to TURP for Benign Prostatic Hyperplasia

BPH-6
Start date: February 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the UroLift System Treatment to Transurethral Resection of the Prostate (TURP) in improving a patient's overall quality of life, while evaluating healthcare expenditures associated with each therapy.

NCT ID: NCT01460342 Completed - Clinical trials for Benign Prostatic Hyperplasia

Phase 3 Study of Tadalafil Once-Daily in Asian Men With Benign Prostatic Hyperplasia (BPH)

Start date: December 2011
Phase: Phase 3
Study type: Interventional

This is a phase 3, randomized, double-blind, placebo-controlled, parallel-design, multinational study to evaluate the efficacy and safety of tadalafil once-a-day dosing for 12 weeks in Asian men with signs and symptoms of benign prostatic hyperplasia.

NCT ID: NCT01454349 Completed - Clinical trials for Benign Prostatic Hyperplasia

Study of PRX302 for Lower Urinary Tract Symptoms Due to Benign Prostatic Hyperplasia (BPH)

Start date: September 2011
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety, tolerability and efficacy of a single treatment of PRX302 for the treatment of Benign Prostatic Hyperplasia (BPH) as compared to placebo.

NCT ID: NCT01438775 Completed - Clinical trials for Benign Prostatic Hyperplasia

Phase 3 Evaluation of Re-Injection of NX-1207 for the Treatment of Benign Prostatic Hyperplasia (BPH)

Start date: September 2011
Phase: Phase 3
Study type: Interventional

This study is designed to demonstrate the safety and efficacy of a second transrectal intraprostatic injection of NX-1207 given to subjects with Benign Prostatic Hyperplasia (BPH) who previously received an injection of NX-1207 in an earlier U.S. clinical trial of NX-1207.