Postoperative Analgesic Efficacy of Continuous Wound Infusion After Laparoscopy — PAIN  

Benign Gynecologic Neoplasm Clinical Trial

Official title: Postoperative Analgesic Efficacy of Continuous Wound Infusion With Local Anesthetics After Laparoscopy (PAIN): a Randomized, Double-blind, Placebo-controlled Trial

Status Recruiting

Clinical Trial Summary

Studies evaluating the effectiveness of continuous wound infusion (CWI) to manage postoperative pain following laparoscopy are markedly lacking. Especially, there was no study comparing CWI and placebo in treating gynecologic laparoscopy. Therefore, the investigators conducted this randomized, double-blind, placebo-controlled trial to investigate whether CWI of local anesthetics was an effective strategy for enhanced recovery after surgery (ERAS), compared with placebo in patients undergoing benign gynecologic laparoscopy.

Clinical Trial Description

Laparoscopic surgery has become an acceptable alternative for open surgery in treating benign gynecologic diseases. One of most important advantages of laparoscopy is a reduced postoperative pain compared with open surgery. Moreover, postoperative pain plays an important part in the enhanced recovery after surgery (ERAS) pathway. Although the length of hospitalization and recovery period after laparoscopy tends to be shorter, postoperative pain can still be an important issue.

Recently, continuous wound infusion (CWI) providing a constant flow of local anesthetic directly a surgical wound postoperatively has been widely used to reduce pain after cesarean section and open surgery. Studies evaluating the effectiveness of CWI to manage postoperative pain following laparoscopy are markedly lacking. Especially, there was no study comparing CWI and placebo in treating gynecologic laparoscopy. Therefore, the investigators conducted this randomized, double-blind, placebo-controlled trial to investigate whether CWI of local anesthetics was an effective strategy for ERAS, compared with placebo in patients undergoing benign gynecologic laparoscopy. ;

Related Conditions & MeSH terms

• Benign Gynecologic Neoplasm
• Genital Neoplasms, Female

• NCT number: NCT03645304
• Study type: Interventional
• Source: Kangbuk Samsung Hospital
• Contact: Taejong Song, MD PhD
• Phone: +821040358405
• Email: taejong.song@gmail.com
• Status: Recruiting
• Phase: N/A
• Start date: January 21, 2019
• Completion date: April 3, 2020