MEVALONATE KINASE GENE MUTATIONS AND THEIR CLINICAL CORRELATIONS IN BEHÇET'S DISEASE

Behçet's Disease Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01780363
• Other study ID #: BH-MVK
• Secondary ID: CUTFBAP25011138C
• Status: Completed
• Phase: N/A
• First received: January 29, 2013
• Last updated: January 29, 2013
• Start date: January 2011

Study information

• Verified date: January 2011
• Source: Cukurova University
• Contact: n/a
• Is FDA regulated: No
• Health authority: Turkey: Ethics Committee
• Study type: Observational

Clinical Trial Summary

Background: Genetics is suggested to play a critical role in the development of Behçet's disease (BD). Shared phenotypic features requires an approach to the differential diagnosis from periodic febrile syndromes particularly from mevalonate kinase deficiency related diseases. We planned to study for evaluating the frequency of mutations and their clinical significance in mevalonate kinase gene in Turkish patients with Behçet's disease.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 0
• Est. primary completion date: December 2011
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Behçet patients

Exclusion Criteria:

• Diagnosis of periodic fever syndromes

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

• Behcet Syndrome
• Behçet's Disease

Locations

Country	Name	City	State
Turkey	Cukurova University	Adana
Turkey	Didem Arslan Tas	Adana

Sponsors (1)

Lead Sponsor	Collaborator
Cukurova University

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Frequency of mevalonate kinase frequency in Behçet disease		One year	No
Secondary	Mevalonate kinase gene and clinical correlations in Behçet's disease		One year	No