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Basal Cell Carcinomas clinical trials

View clinical trials related to Basal Cell Carcinomas.

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NCT ID: NCT04389112 Recruiting - Clinical trials for Cutaneous Squamous Cell Carcinoma

Study of Metabolic Changes in the Transformation Malignant Precancerous Skin Lesions

MITOSKIN
Start date: February 28, 2020
Phase: N/A
Study type: Interventional

Skin carcinomas are the most frequent cancers in the world, including basal cell carcinomas and cutaneous squamous cell carcinoma (cSCCs), with more than 60.000 new annual cases in France. Their incidence increases mainly due to ultraviolet (UV) exposure and population ageing. Then from 1994 to 2006, the incidence of cSCC has increased by 300%. CSCCs typically manifests as a spectrum from a precursor actinic keratosis (AK) - possible spontaneous regression at this stage- to in situ cSCC invasive cSCC and finally metastatic cSCC.

NCT ID: NCT02828111 Completed - Clinical trials for Basal Cell Carcinomas

Clinical Trial of Patidegib Gel 2%, 4%, and Vehicle Applied Once or Twice Daily to Decrease the GLI1 Biomarker in Sporadic Nodular Basal Cell Carcinomas

BCC
Start date: November 11, 2016
Phase: Phase 2
Study type: Interventional

This is a double-blind, dose escalating, randomized, vehicle-controlled study designed to compare the efficacy and safety of patidegib gel 2% and 4% applied once or twice daily in comparison with that of vehicle in patients with Basal Cell Carcinoma. One investigational center (metasite) in the United States will participate in this study. Approximately 36 subjects who meet the study entry criteria will be enrolled into one of four sequential cohorts. Within each cohort subjects will be randomized in a 2:1 ratio to receive active or vehicle gel.

NCT ID: NCT02067104 Terminated - Clinical trials for Basal Cell Carcinomas

Vismodegib in Basal Cell Carcinomas (BCC) Chemoprevention

Start date: February 17, 2014
Phase: Phase 2
Study type: Interventional

This study is a single site double blinded Phase II study to evaluate the chemopreventative effectiveness of vismodegib in the treatment of subjects at high risk for developing basal cell carcinomas (BCC).

NCT ID: NCT01463709 Completed - Clinical trials for Basal Cell Carcinomas

Development of a Nanosecond Pulsed Electric Field System to Treat Skin Cancer

NPEF
Start date: October 2011
Phase: Phase 1
Study type: Interventional

Human Basal Cell Carcinomas (BCCs) can be ablated by treating them with nanosecond pulsed electric fields (nsPEF)

NCT ID: NCT01349361 Recruiting - Clinical trials for Photodynamic Therapy

Treatment of Basal Cell Carcinomas With Methyl Aminolevulinate and Daylight

Start date: March 2011
Phase: Phase 2
Study type: Interventional

Photodynamic Therapy (PDT) is an effective treatment of basal cell carcinomas (BCC) however the inconvenience of clinic attendance and discomfort during therapy are significant drawbacks. The objective of this study is to evaluate the effect of daylight-mediated PDT of BCC.