Polar Wand Carbon Dioxide Cryotherapy for Barrett's Esophagus

Status Terminated

Clinical Trial Summary

The purpose of this pilot study is to provide an initial assessment of the feasibility, safety and efficacy of Polar Wand carbon dioxide cryotherapy for treatment of Barrett's low grade and high grade dysplasia by use in a small number of patients so as to support, or otherwise, the development of a full-scale trial.

Clinical Trial Description

Prospective pilot study to be performed in 14 Barrett's Esophagus patients with low grade and high grade dysplasia, referred for standard of care treatment. Patients will receive treatments with carbon dioxide Polar Wand cryotherapy at 0, 2 and 4 months, followed by surveillance endoscopy with four quadrant biopsies throughout the entire Barrett's esophagus (BE)segment at 6 months, followed by endoscopy with additional treatments (if needed) at 8 and 10 months, followed by a final surveillance endoscopy at 12 months, with four quadrant biopsies throughout the entire initial BE segment length. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01477177
Study type	Interventional
Source	Mayo Clinic
Contact
Status	Terminated
Phase	N/A
Start date	August 2011
Completion date	April 2014

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