PPI Therapy Impact on GERD After Sleeve Gastrectomy

Status Not yet recruiting

Clinical Trial Summary

The trial would to try to establish:

- The best post-operative PPI prescription protocol after Sleeve Gastrectomy

- The impact of PPI therapy on postoperative peptic diseases (erosive gastropathies, ulcers, duodenitis, esophagitis and/or Barrett)

- The impact of PPI therapy on post-operative GERD symptoms (assessed with the use of two standard tests: MRGE-HRQL and GERDQ

Clinical Trial Description

45 patients candidate to primary SG and randomized in 3 study groups (15 per group) GROUP A: no treatment (control group)

GROUP B (standard dose-long term): Lansoprazole buccal tablets 30 mg once daily (before breakfast on an empty stomach) for 6 months

GROUP C (standard dose-short term): Lansoprazole buccal tablets 30 mg once daily (before breakfast on an empty stomach) for 3 months ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04400136
Study type	Interventional
Source	University of Roma La Sapienza
Contact
Status	Not yet recruiting
Phase	Early Phase 1
Start date	July 1, 2020
Completion date	September 1, 2022

View Details

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