Clinical Trial Details
— Status: Active, not recruiting
Administrative data
| NCT number |
NCT03828513 |
| Other study ID # |
KIA 2018/174 |
| Secondary ID |
|
| Status |
Active, not recruiting |
| Phase |
N/A
|
| First received |
|
| Last updated |
|
| Start date |
March 1, 2018 |
| Est. completion date |
October 1, 2024 |
Study information
| Verified date |
June 2024 |
| Source |
Kocaeli Derince Education and Research Hospital |
| Contact |
n/a |
| Is FDA regulated |
No |
| Health authority |
|
| Study type |
Interventional
|
Clinical Trial Summary
Evaluate the effects of high-flow nasal oxygen therapy on atelectasis in the perioperative
period by lung ultrasound (LUS) in bariatric surgery patients.
Description:
In obese patients, lung compliance decreases by 25% and Functional Residual Capacity
decreases by about one-third. As they consume about 25% more oxygen than non-obese
individuals, postoperative pulmonary complications occur more commonly. POINT (Peri-Operative
Insufflatory Nasal Therapy) provides humidified and heated high flow oxygen therapy in
perioperative period. High-flow nasal oxygen (HFNO) facilitates oxygenation and ventilation of
both the spontaneously breathing and apnoeic patient.High-flow nasal cannula oxygen came to
prominence in anaesthesia when it was shown to prolong the time to oxygen desaturation in
patients with a difficult airway.
Lung ultrasonography (LUS) has been used more frequently in the diagnosis of pulmonary
pathologies than chest radiography. This prospective observational study is to evaluate the
effects of high-flow nasal oxygen therapy on atelectasis in the perioperative period by lung
ultrasound (LUS) in bariatric surgery patients.
Materials and Methods: Following the Ethics Committee approval and written informe consents,
100 adult bariatric surgery patients are include in this observational study. The patients
are randomly distributed into two groups ; High Flow Nasal Cannula Oxygenation(HFNCO) made
group(n:50); HFNCO not made group(n:50).
HFNCO is start at a flow rate of 20 L/min with 100% oxygen in the preoperative period. It is
titrate up to 50 L/min and increase to 80 L/min under general anesthesia until tracheal
intubation. Atelectasis evaluation with lung ultrasound is performe and score in 6 different
areas before and after HFNCO.
Pulmonary function tests and blood gas parameters are compared.During the procedure, the
patient's blood pressure, heart rate, oxygen saturation, any complications that may develop
will be recorded.nduction of anesthesia; difficult airway management, difficult mask and / or
difficult intubation incidence, Mallampati scores, the use of one of the difficult intubation
techniques during intubation (such as FastTrack, videolaryngoscopy or fiberoptic intubation),
perioperative mechanical ventilation parameters (ventilation mode, tidal volume, respiratory
frequency, end of tidal CO2 (carbon dioxide) pressure, PEEP usage, SpO2 (saturation oxygen),
airway peak pressure, urine volume, arterial blood gas parameters are recorded.Duration of
operation, surgical method (laparotomy / laparoscopy), agents used in induction and
postoperative analgesia, use of blood, blood product and vasopressor are recorded.
