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Pilot Study for Zoledronic Acid to Prevent Bone Loss After Bariatric Surgery

Bariatric Surgery Candidate Clinical Trial

Official title:
Pilot Study for Zoledronic Acid to Prevent High-Turnover Bone Loss After Bariatric Surgery

Clinical Trial Summary

This study evaluates whether zoledronic acid can prevent the high bone turnover that occurs after Roux-en-Y Gastric Bypass (RYGB) and sleeve gastrectomy (SG) surgery.

Clinical Trial Description

The investigators are evaluating the ability of a single dose of zoledronic acid to improve bone outcomes after RYGB or SG surgery. The investigators have previously shown that RYGB and SG have negative effects on bone density, bone microarchitecture, and that bariatric procedures potentially increase the risk of fractures. The purpose of this study is to evaluate the safety and efficacy of zoledronic acid to prevent the high-turnover bone loss that occurs in adults who have chosen to undergo RYGB or SG. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03424239
Study type Interventional
Source Massachusetts General Hospital
Contact
Status Completed
Phase Phase 4
Start date August 1, 2018
Completion date January 1, 2020
View Details
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