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Study to Compare the Bioavailability of Omeprazole 20 mg Before and After Undergoing Surgery for Morbid Obesity — OBS-2011/001  

Bariatric Surgery Candidate Clinical Trial

Official title:
Bioavailability Study of Omeprazole (20 mg) at Steady State (Multiple Dose) in Patients Who Have Undergone Bariatric Surgery

Clinical Trial Summary

The principal aim was to evaluate whether gastric bypass surgery modifies the bioavailability of omeprazole 20 mg at one month and six months after surgery.

Other objectives were:

- To compare bioavailability of omeprazole 20 mg between patients undergo gastric bypass surgery and patients who avoid it.

- To asses other pharmacokinetic parameters, demographic parameters and drug safety.

Study design It was planned a mixed design which intended to compare the bioavailability in patients with gastric bypass (before and after surgery) and control subjects matched by sex and body mass index (BMI) post-surgery. This was a single-dose, open-label, crossover bioavailability study of omeprazole in surgical group and controls.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03378960
Study type Interventional
Source Hospital San Carlos, Madrid
Contact
Status Completed
Phase Phase 4
Start date October 31, 2014
Completion date February 29, 2016
View Details
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