Badly Decayed Teeth Clinical Trial
Official title:
The Effect on Dental Implant Stability With and Without Using 1:1 Mixture of Autogenous Bone and Anorganic Bovine Bone Minerals Particulates in Immediate Implant Placement in the Dental Esthetic Zone (A Randomized Clinical Trial)
Xenografts are graft materials derived from the inorganic portion of animal bones; the most
common source is bovine the removal of the organic component are processed to remove their
antigenicity, while the remaining inorganic components provide a natural matrix as well as an
excellent source of calcium. The disadvantage of xenografts is that they are only
osteoconductive and the resorption rate of bovine cortical bone is slow.
However leaving the jumping gap empty has been the gold standard for immediate implantation
as the formed blood clot will allow bone fill in that area.
Not using a grafting material in the jumping gap was chosen as a comparator as it's the
standard procedure usually applied and showed high success rates. This should allow us to
assess whether the chosen grafting material would have a positive influence on the study
outcomes as compared to it.
Intraoral and extraoral autologous bone grafts could be considered as the "Gold standard"
pre-prosthetic dentoalveolar reconstruction of atrophic jaws with cortico-cancellous bone
grafts from intraoral and/or extraoral donor sites as a predictable technique for the
facilitation of dental rehabilitation of atrophic ridges, associated with high bone survival
rate and long term implant success. Autogenous bone corresponds to bone graft obtained from
the same individual. It is considered the gold standard for filling of bone defects since it
allows (I) osseointegration: direct contact with bone tissue without fibrous tissue ; (II)
osteoconduction: support to bone growth (III) osteoinduction: differentiation of mesenchymal
cells of surrounding tissue (receptor site) into osteoblastic cells ; and (IV) osteogenesis:
bone neoformation by osteoblastic cells present in the graft material. Although few mature
osteoblasts survive to grafting, precursor cells are responsible for the osteogenic potential
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT04738513 -
One Year Clinical Evaluation of New Gradient Technology Monolithic Zirconia (5Y-TZP/3Y-TZP) Crowns in Dental Esthetic Zone With Vertical Versus Conventional Preparation Techniques
|
N/A |