Effectiveness of Different Candies Against Bad Breath

Bad Breath Clinical Trial

— HALIDROP  

Official title:

Effectiveness of Different Candies Against Bad Breath

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04589481
• Other study ID #: 2020-01943; ex20Filippi
• Status: Completed
• Phase: N/A
• Start date: February 23, 2021
• Est. completion date: June 1, 2021

Study information

• Verified date: June 2021
• Source: University Hospital, Basel, Switzerland
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study is to analyze whether the candies can relieve or eliminate bad breath, both subjectively and objectively.

Description:

This study is to systematically examine an existing candy, which is easily available and is intended to relieve or eliminate bad breath. The main aim of the study is to determine the effectiveness of the candies on the subjective perception of bad breath. The secondary outcome of the study is to investigate whether there is actually a decrease in volatile sulphur compounds (VSC) in the exhaled air and also a decrease in bad breath during organoleptic measurement.

The purpose of the study is to investigate whether the different candies can relieve or eliminate bad breath, both subjectively and objectively.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 35
• Est. completion date: June 1, 2021
• Est. primary completion date: June 1, 2021
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 40 Years

Eligibility

Inclusion Criteria:

• Non- smoker

• No general medical illness or medication

Exclusion Criteria:

• Allergies/intolerances to ingredients of the products used

• Chronic diseases

• Smoker

• Pregnancy

Related Conditions & MeSH terms

• Bad Breath
• Halitosis

Intervention

Other:
• Intake of 3 different candies against bad breath
Intake of 3 different candies against bad breath on three different days (2-days interval each) after artificially creating a temporary bad breath (by eating of chips and cheese); analysis of breathing during intake of candy both subjectively and objectively

Locations

Country	Name	City	State
Switzerland	Universitäres Zentrum für Zahnmedizin UZB	Basel

Sponsors (2)

Lead Sponsor	Collaborator
University Hospital, Basel, Switzerland	Ricola Group AG Schweiz

Country where clinical trial is conducted

Switzerland, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Organoleptic analysis of breathing air sample	Assessment of the patient's bad breath on the basis of the subjective assessment of an investigator (scale of 0 to 5 (0, no odor; 1, questionable odor; 2, slight malodor; 3, moderate malodor; 4, strong malodor; 5, severe malodor))	max 60 minutes at 3 different days
Primary	Measurement of volatile sulphur compounds (VSC) in ppb (parts per billion).	Assessment of the patient's bad breath on the basis of the objective assessment by a sulfide monitor (HaliSens® AI Analytical Innovations GmbH, Moosbach, Germany)	max 60 minutes at 3 different days