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Population Pharmacokinetics of Commonly Used Antimicrobial Agents in Children of Bacterial Meningitis With Augmented Renal Clearance

Bacterial Meningitis Clinical Trial

Official title:
Population Pharmacokinetics of Commonly Used Antimicrobial Agents in Children of Bacterial Meningitis With Augmented Renal Clearance

Clinical Trial Summary

The investigator's purpose is to study the population pharmacokinetics of commonly used antimicrobial agents in children of bacterial meningitis with augmented renal clearance and assess dosage individualization feasibility.

Clinical Trial Description

The investigator's purpose is to study the population pharmacokinetics of meropenem, vancomycin, ceftazidime, ceftriaxone, ceftizoxime and linezolid in children of bacterial meningitis with augmented renal clearance and assess dosage individualization feasibility. In this study, the investigator will detect drug concentration in both plasma and cerebrospinal fluid to construct population pharmacokinetics. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04771884
Study type Observational
Source Shandong University
Contact Wei Zhao, Phd
Phone 86053188383308
Email zhao4wei2@hotmail.com
Status Recruiting
Phase
Start date October 1, 2020
Completion date March 20, 2026
View Details
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