Oral Surgery Clinical Trial
Official title:
Randomized Clinical Trial of Microbial Growth in the Suture Thread, After the Post-surgical Application of Different Antiseptic Gels in Mandibular Third Molars Extraction
This is a randomized clinical trial in which investigators will compare the antimicrobial
effect and inducer of cicatrization as well as the degree of postoperative pain in patients
who are extracted the lower third molars.
After the surgery, different bioadhesive gels will be applied in the area of the surgical
wound and we will evaluate the aforementioned parameters.
Introduction: Surgical removal of the third molars is one of the most frequent procedures in
oral surgery. Healing of the wound is initially sought by approximating the edges using a
suturing technique. Adherence and microbiological accumulation of the suture during the
period that it remains in the mouth, which can serve as a focus for odontogenic infections.
The use of oral antiseptics before and after the surgery is an efficient method for
microbial reduction. The purposes of this project were to evaluate the microbial growth in
the suture thread on different culture means after the post-surgical application of the gels
under study, while assessing the intensity of post-surgical pain and the degree of healing
of the surgical wound.
Material and methods: It is a randomized and blind clinical trial. 21 patients participated
(42 wisdom teeth), who consulted the unit for a surgical tooth extraction for at least the
two lower wisdom teeth. The evaluated bioadhesive gels were: Chlorhexidine gel at 0.2 %
(Bexident Gel Gingival®), Chlorhexidine gel at 0.2% + Chitosan (Bexident Post®) and
hyaluronic acid gel (ODDENT®). A neutral water-based gel without any active ingredients was
also used HISPAGEL 200® (Acofarma, Madrid, Spain) as the control agent. An assessment of the
post-surgical healing, the microbiological analysis of the suture thread and the
post-surgical pain was developed.
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