Contamination of Bacillus Species Sepsis.

Bacillus Cereus Infection Clinical Trial

— BACILLUS  

Official title:

Contamination of Bacillus Species Sepsis.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03377530
• Other study ID #: CHRD1715
• Status: Completed
• Start date: January 1, 2008
• Est. completion date: August 31, 2016

Study information

• Verified date: July 2019
• Source: Centre Hospitalier René Dubos
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Bacillus species are ubiquitous gram-positive spore-forming organisms. They rarely cause disease in the immunocompetent and are more frequently isolated as a culture contaminant. However, Bacillus Species can cause severe systemic infections in immunocompromised patients including preterm infants.

The purpose of this study is to identify the risk factors of these infections.

Description:

Non-anthrax Bacillus Species bacteria can be responsible for food poisoning and local infections. Rarely, they lead to severe infections like blood stream infections and meningitis especially in immunocompromised patients like preterm infants.

Bacillus Cereus is the most common members of the genus Bacillus. Only few reports studied these systemic infections in premature neonates. In order to identify the risk factors for severe Bacillus Species infections, we studied retrospectively eleven cases of these infections in our NICU and reviewed series and report cases in literature.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 11
• Est. completion date: August 31, 2016
• Est. primary completion date: August 31, 2016
• Gender: All
• Age group: N/A to 28 Days

Eligibility

Inclusion Criteria:

• cases of Bacillus Species sepsis

• cases of Bacillus species meningitis

• with significant change in clinical status

• Bacillus Species is the only organism isolated

Exclusion Criteria:

• Bacillus Species isolated with other organisms and Bacillus Species without clinical change were considered to be contaminants

Related Conditions & MeSH terms

• Bacillus Cereus Infection

Intervention

Diagnostic Test:
• Ways to prevent these infections.
The purpose of this database is to describe the pathogenicity of this germ, the incriminated modes of contamination. The collaborators studied the factors of poor prognosis and propose ways to prevent these infections.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Centre Hospitalier René Dubos

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Severe infection rate due to Bacillus Sp germ	The purpose of this database is to mesure the pathogenicity of this germ based on the severe infection rate	Through study completion, an average of 1 year.
Secondary	To collecte the incriminated modes of contamination.	The purpose of this database is to describe the incriminated modes of contamination.	Through study completion, an average of 1 year.