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Clinical Trial Summary

A Multicenter, Open-label, Phase I Study to Evaluate the Safety, Pharmacokinetics, and Preliminary Efficacy of HMPL-760 in Patients with Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma


Clinical Trial Description

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary efficacy of HMPL-760 administered orally in subjects with relapsed/refractory B-cell non-Hodgkin lymphoma (B-NHL). Patients with relapsed/refractory B-NHL, including chronic lymphocytic leukemia/small cell lymphoma (CLL/SLL), diffuse large B-cell lymphoma (DLBCL), follicular cell lymphoma (FL), mantle cell lymphoma (MCL), marginal zone lymphoma (MZL), and lymphoplasmacytic/macroglobulinemia (LPL/WM). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05190068
Study type Interventional
Source Hutchmed
Contact Jian Chen, Ph.D
Phone 021-20671942
Email Jianc2@hutch-med.com
Status Recruiting
Phase Phase 1
Start date January 4, 2022
Completion date April 2026

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