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Clinical Trial Summary

This is a single arm, open-label, early phase I study, to determine the safety and efficacy of Novel CAR-T cell therapy in Hematological Malignancy treatment.


Clinical Trial Description

The Novel CAR-T contains either a scFv plus a PD-L1 blocker, or two scFvs, in a cytokine complex based outer memberane structure, this kind of structure enables the CAR-T cells to simultaneously target one or two targets on the tumor cell surface and enhance CAR-T cell persistence in tumor microenvironment,as well as stimulating innate T/NK cell activation and expansion. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04191941
Study type Interventional
Source Timmune Biotech Inc.
Contact Ming Zhou
Phone +86 0731 83928147
Email zhouming_0321@163.com
Status Recruiting
Phase Early Phase 1
Start date September 1, 2019
Completion date December 31, 2021

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