Prognosis Of Patients With Aggressive B-Cell Lymphoma, Treated With Rituximab+Anthracycline Regimen

B-Cell Lymphomas Clinical Trial

— ProDLBCL  

Official title:

Prognosis Of Patients With Aggressive B-Cell Lymphoma, Treated With Rituximab+Anthracycline Regimen (ProDLBCL)

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01478269
• Other study ID #: IIL_ProDLBCL
• Status: Completed
• Phase: N/A
• First received: October 12, 2011
• Last updated: November 22, 2011
• Start date: May 2009
• Est. completion date: May 2011

Study information

• Verified date: November 2011
• Source: Fondazione Italiana Linfomi ONLUS
• Contact: n/a
• Is FDA regulated: No
• Health authority: Italy: The Italian Medicines Agency
• Study type: Observational

Clinical Trial Summary

This study is a retrospective analysis of an homogeneous population of patients with aggressive B-cell lymphoma and treated upfront with R-CHOP or R-CHOP like regimens to reassess the prognostic factors and hopefully to identify more accurate prognostic subgroups with a clinical and therapeutical relevance.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 1927
• Est. completion date: May 2011
• Est. primary completion date: May 2011
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

1. Histologically confirmed newly diagnosed aggressive B-cell lymphoma according to the current World Health Organisation Classification, from 2001 to 2007.

2. Any stage of disease.

3. Treatment with R-CHOP or R-CHOP like regimens (+/- transplant).

4. Age at least 18 years.

5. Availability of tissue biopsy at diagnosis for a possible centralized revision.

6. Availability of data on clinical involvement, laboratory, treatment and follow up.

Exclusion Criteria:

Study Design

Observational Model: Cohort, Time Perspective: Retrospective

Related Conditions & MeSH terms

• B-Cell Lymphomas
• Lymphoma
• Lymphoma, B-Cell

Locations

Country	Name	City	State
Brazil	Hemocentro-Unicamp	Campinas
Brazil	Centro Medico	Santa Isabel
Brazil	Centro Paulista de Oncologia	Sao Paolo
Brazil	Santa Casa Medical School	Sao Paolo
Italy	A.O.SS. Biagio, Antonio e Cesare Arrigo	Alessandria
Italy	Centro di riferimento Oncologico Oncologia Medica A	Aviano (Pordenone)
Italy	USC Ematologia e Trapianto di Midollo Osseo Ospedali Riuniti di Bergamo	Bergamo
Italy	Presidio Ospedaliero A.Perrino - Divisione di Ematologia	Brindisi
Italy	U.O. di Oncologia Ospedale di Circolo di Busto Arsizio	Busto Arsizio
Italy	Ospedale Civile	Camposanpiero (PD)
Italy	A.O.Pugliese Ciaccio Diviisone di Ematologia	Catanzaro
Italy	Presidio Ospedaliero Annunziata U.O.C. di Ematologia	Cosenza
Italy	Clinica Ematologica Policlinico Carreggi	Firenze
Italy	Ematologia 1 Ospedale S. Martino	Genova
Italy	Oncologia Medica B e C IST Genova	Genova
Italy	Ospedale Felettino	La Spezia
Italy	Ospedale Madonna delle grazie U.O. Ematologia	Matera
Italy	A O Papardo	Messina
Italy	Azienda Ospedaliero Universitaria Policlinico Gaetano Martino	Messina
Italy	Ematologia e Trapianto IRCCS, Istituto Nazionale dei Tumori	Milano
Italy	Oncologia Medica 3 Istituto Nazionale dei Tumori di Milano	Milano
Italy	Osp. San Carlo Borromeo Divisione di Oncologia Medica	Milano
Italy	Ospedale Maggiore IRCCS-Dipartimento di Ematologia	Milano
Italy	Centro Oncologico Modenese	Modena
Italy	A.O. Maggiore della Carità S.C.D.U. Ematologia	Novara
Italy	A.O. di Padova Divisione di Oncologia Medica	Padova
Italy	Casa di cura La Maddalena Unita' di Ematologia	Palermo
Italy	Div. di Ematologia e TMO AOU Policlinico Giaccone di Palermo	Palermo
Italy	A O Universitaria di Parma	Parma
Italy	Ospedale Civile G.da Saliceto - UOA Ematologia	Piacenza
Italy	Azienda Ospedaliero Universitaria Pisana U.O. Ematologia	Pisa
Italy	AO Bianchi Melacrino Morelli UO Ematologia	Reggio Calabria
Italy	AO Arcispedale S.Maria Nuova Ematologia	Reggio Emilia
Italy	Ospedale Oncologico regionale CROB	Rionero in Vulture (PZ)
Italy	Dipartimento di biotecnologie cellulari ed ematologia Ospedale Umberto I - La Sapienza	Roma
Italy	Policlinico A. Gemelli Università Cattolica del Sacro Cuore	Roma
Italy	Clinica Humanitas	Rozzano (MI)
Italy	A.O.San Giovanni Battista	Torino
Italy	U.O. Oncologia Azienda ULSS7 P.O. di Vittorio Veneto	Vittorio Veneto

Sponsors (1)

Lead Sponsor	Collaborator
Fondazione Italiana Linfomi ONLUS

Countries where clinical trial is conducted

Brazil,  Italy,