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Clinical Trial Summary

It is a single-center, open-labeled, single-arm, non-randomized, investigator-initiated trial aiming to evaluate the efficacy and safety of anti-CD19 CAR-T manufactured by OlyCAR platform (OlyCAR-019) for CD19+ refractory/relapsed B-Cell malignancies.


Clinical Trial Description

OlyCAR is a novel CAR-T manufacturing system which allows to generate clinical-use CAR-T cells in short time. This study is going to evaluate the feasibility of CAR-T manufactured by OlyCAR platform in the treatment of B-Cell malignancies. The OlyCAR-019 cells will be infused by vein. Subjects will be followed for safety and efficacy up to 12 weeks. For those with a durable remission 12 weeks after infusion, the follow-up will last for at least 12 months for disease control. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05932173
Study type Interventional
Source 920th Hospital of Joint Logistics Support Force of People's Liberation Army of China
Contact Sanbin Wang, Professor
Phone 13187424131
Email Sanbin1011@163.com
Status Recruiting
Phase Phase 1/Phase 2
Start date July 1, 2023
Completion date June 30, 2025

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