B-cell Lymphoma Clinical Trial
Official title:
Phase II Study of Evaluation of Fractionated Radio-immunotherapy With 90Y-DOTA-hLL2 as a Consolidation Therapy After First Line of Chemotherapy in Patients Older Than 60 With Disseminated Diffuse Large B-cell Lymphoma
Phase II, multi-centric, open-label, study.
Disseminated diffuse large B-cell lymphoma in patients older than 60: evaluation of
fractionated radio-immunotherapy with 90Y-DOTA-hLL2 as a consolidation therapy after first
line of chemotherapy.
Initial treatment: 6 courses of CHOP-R 14 with evaluation of response before C4 (observation
of no change or progression at this time will get the patient off study).
Consolidation : fractionated RIT (8 weeks after the end of R-CHOP: 2 injections of 15 mCi/m2
of 90Y-DOTA-hLL2 and hLL2 at day 1 and day 8).
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