A Study of Novel Anti-CD19 CAR-T in Patients With r/r B-Cell Malignancies

Status Recruiting

Clinical Trial Summary

It is a single-center, open-labeled, single-arm, non-randomized, investigator-initiated trial aiming to evaluate the efficacy and safety of anti-CD19 CAR-T manufactured by OlyCAR platform (OlyCAR-019) for CD19+ refractory/relapsed B-Cell malignancies.

Clinical Trial Description

OlyCAR is a novel CAR-T manufacturing system which allows to generate clinical-use CAR-T cells in short time. This study is going to evaluate the feasibility of CAR-T manufactured by OlyCAR platform in the treatment of B-Cell malignancies. The OlyCAR-019 cells will be infused by vein. Subjects will be followed for safety and efficacy up to 12 weeks. For those with a durable remission 12 weeks after infusion, the follow-up will last for at least 12 months for disease control. ;

Study Design

Related Conditions & MeSH terms

B-Cell Leukemia
B-Cell Lymphoma
Leukemia, B-Cell
Leukemia, Lymphocytic, Chronic, B-Cell

Clinical Trial Details

NCT number	NCT05932173
Study type	Interventional
Source	920th Hospital of Joint Logistics Support Force of People's Liberation Army of China
Contact	Sanbin Wang, Professor
Phone	13187424131
Email	Sanbin1011@163.com
Status	Recruiting
Phase	Phase 1/Phase 2
Start date	July 1, 2023
Completion date	June 30, 2025

View Details

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