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Efficacy and Safety of Namilumab for Moderate-to-severe Axial Spondyloarthritis — NAMASTE  

Axial Spondyloarthritis Clinical Trial

Official title:
A Phase 2a Study to Evaluate the Safety and Efficacy of Namilumab in Subjects With Moderate-to-severely Active Axial Spondyloarthritis

Clinical Trial Summary

The study will assess the effect of namilumab, a GM-CSF inhibitor, on the clinical response in subjects with axial spondyloarthritis. Subjects will receive treatment with either namilumab or placebo.

Clinical Trial Description

A phase 2a proof-of-concept, randomised, double-blind, placebo-controlled study to evaluate the safety/tolerability and efficacy of 4 subcutaneous injections of namilumab (150 mg) given over 10 weeks in subjects with moderate-to-severely active axial spondyloarthritis including those previously exposed to anti- TNF therapy (NAMASTE study). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03622658
Study type Interventional
Source Izana Bioscience Ltd.
Contact
Status Completed
Phase Phase 2
Start date September 6, 2018
Completion date February 4, 2020
View Details
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