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Axial Spondyloarthritis (axSpA) clinical trials

View clinical trials related to Axial Spondyloarthritis (axSpA).

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NCT ID: NCT04089514 Completed - Clinical trials for Crohn's Disease (CD)

A Real-world Study of Imraldi® Use

PROPER
Start date: June 30, 2019
Phase:
Study type: Observational

The primary objective of this study is to evaluate candidate predictors of persistence on adalimumab (Imraldi®) participants diagnosed with immune-mediated inflammatory disease in Europe (EU). The secondary objectives of this study are to describe participant clinical characteristics at baseline, utilization of Imraldi® over time, biologic drug effectiveness over time, participant satisfaction with biologic administration, routine laboratory values and clinical evaluation measurements over time, use of relevant concomitant medication use over time, immunogenicity of biosimilars and to summarize safety events.

NCT ID: NCT03322618 Completed - Clinical trials for Ankylosing Spondylitis (AS)

Evaluation of the Expression and Functions of the KIR3DL2 Receptor and the Anti-inflammatory Activity of IPH4102 in Blood Samples

KIR3DL2
Start date: December 18, 2017
Phase: N/A
Study type: Interventional

the main objectives are 1. to study the pathophysiological role of KIR3DL2 in axSpA and its relationship with Th17 immunity in HLA-B27 + and HLA-B27- patients and 2. to assess the effect on the pro-inflammatory immune response of a cytotoxic monoclonal antibody IPH4102 (anti-KIR3DL2) in these patients. The study will be carried out on blood samples from 24 patients with axSpA, 12 HLA-B27 + and 12 HLA-B27-, without any drug injection nor direct therapeutic benefit for the participating patients and 12 healthy controls.

NCT ID: NCT03020992 Completed - Clinical trials for Axial Spondyloarthritis (axSpA)

A Study to Assess the Effects of Certolizumab Pegol on the Reduction of Anterior Uveitis (AU) Flares in Axial Spondyloarthritis Subjects With a Documented History of AU

C-VIEW
Start date: December 21, 2016
Phase: Phase 4
Study type: Interventional

The purpose of the study is to demonstrate the effect of Certolizumab Pegol (CZP) treatment on the reduction of Anterior Uveitis (AU) flares in subjects with active axial Spondyloarthritis (axSpA) and a documented history of AU.

NCT ID: NCT02154425 Completed - Clinical trials for Rheumatoid Arthritis

A Multicenter, Postmarketing Study Evaluating the Concentration of Cimzia® in Mature Breast Milk of Lactating Mothers

CRADLE
Start date: September 2014
Phase: Phase 1
Study type: Interventional

The primary objectives of this study are to assess whether there is transfer of Certolizumab Pegol (CZP) into breast milk of lactating mothers who are receiving an established dosing regimen of CZP by evaluating the concentration of CZP in mature breast milk, and to calculate the daily infant dose of maternal CZP.

NCT ID: NCT02019602 Completed - Clinical trials for Rheumatoid Arthritis

A Multicener, Postmarketing Study Evaluating the Transfer of Cimzia From the Mother to the Infant Via the Placenta

CRIB
Start date: January 2014
Phase: Phase 1
Study type: Interventional

The primary purpose is to assess whether there is transfer of Certolizumab Pegol (CZP) from pregnant women receiving treatment with Cimzia® across the placenta to infants by evaluating the concentration of CZP in the plasma of infants at birth.