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AV Fistula clinical trials

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NCT ID: NCT02475837 Completed - AV Fistula Clinical Trials

Vorapaxar Study for Maturation of AV Fistulae for Hemodialysis Access

Start date: August 26, 2015
Phase: Phase 2
Study type: Interventional

The Objectives of this study are: 1. To determine if vorapaxar safely improves arteriovenous (AV) fistula functional maturation when administered during the maturation process compared with placebo. 2. To determine if vorapaxar safely improves AV fistula patency, allowing for secondary procedures to aid in fistula maturation compared with placebo. 3. To determine if vorapaxar safely facilitates successful cannulation of AV fistulas for hemodialysis compared with placebo. This is a randomized placebo-controlled double-blind pilot trial. Study procedures will be conducted at Stanford University Medical Center, and standard-of-care (SOC) procedures will be conducted at Stanford and it's affiliated hospitals (Veteran's Affairs Palo Alto Health Care System and the Stanford Vascular Surgery Clinic at Valley Medical Center). The investigators expect to enroll 128 patients. Patients will be assigned to treatment groups with a 1:1 randomization in blocks of 4 at the conclusion of the AV fistula creation. Patients will be stratified based on fistula location (lower arm versus upper arm).

NCT ID: NCT02363972 Completed - Clinical trials for End Stage Renal Disease

Percutaneous Less Invasive AV Fistula for Vascular Access in ESRD

Start date: February 10, 2015
Phase: N/A
Study type: Interventional

A prospective single-arm well-controlled study to evaluate the safety and effectiveness of a less invasive means of establishing vascular access to facilitate dialysis in patients with end stage renal disease.

NCT ID: NCT01471041 Completed - Clinical trials for End Stage Renal Disease

Safety and Efficacy Study of the Venous Window Needle Guide to Access Arteriovenous (AV)Fistulae

SAVE
Start date: December 2011
Phase: Phase 2/Phase 3
Study type: Interventional

The SAVE Study will evaluate the safety and efficacy of the Venous Window Needle Guide in achieving access of a deep, un-cannulatable arteriovenous fistula to complete hemodialysis as prescribed.