Clinical Trials Logo

Clinical Trial Summary

This study will be investigating the effects of fesoterodine on autonomic dysreflexia (AD) in patients with spinal cord injuries (SCI). The goal of the study is to examine the effect of increasing daily use of fesoterodine on episodes of high blood pressure triggered by urinary bladder contractions.


Clinical Trial Description

This is a Phase 2, open-label exploratory study investigating the efficacy of fesoterodine for treatment of adult patients with spinal cord injuries (SCI) with autonomic dysreflexia (AD) triggered by neurogenic detrusor overactivity (NDO). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02676154
Study type Interventional
Source University of British Columbia
Contact
Status Completed
Phase Phase 2
Start date February 25, 2016
Completion date January 31, 2019

See also
  Status Clinical Trial Phase
Not yet recruiting NCT05635851 - NO AD: Use of Nitric Oxide (NO) Donors for the Prevention of Autonomic Dysreflexia (AD) During Bowel Care Following SCI Phase 2
Recruiting NCT05351827 - Mild Intermittent Hypoxia: A Prophylactic for Autonomic Dysfunction in Individuals With Spinal Cord Injuries N/A
Completed NCT03307161 - Osteopathic Manual Treatment Parkinson's Disease and Truncal Dystonia N/A
Recruiting NCT04493372 - Deciphering Preserved Autonomic Function After Spinal Cord Injury N/A
Not yet recruiting NCT06211491 - Autonomic Dysreflexia in Spinal Cord Injuries: UDS Filling Speed Impact
Completed NCT02919917 - Treatment of Post-SCI Hypotension Phase 2/Phase 3
Recruiting NCT05380661 - Heart Rate Variability and Anxiety During Urinary Bladder Catheterization N/A
Recruiting NCT04193709 - Recovery of Bladder and Sexual Function After Human Spinal Cord Injury N/A
Recruiting NCT05024487 - Prevention of Complications Due to Autonomic Dysreflexia in SCI Individuals N/A
Completed NCT04858178 - Transcutaneous Spinal Cord Neuromodulation to Normalize Autonomic Phenotypes N/A
Not yet recruiting NCT03924388 - Spinal Cord Stimulation and Autonomic Response in People With SCI. N/A
Completed NCT02893553 - The Effects of Normalizing Blood Pressure on Cerebral Blood Flow in Hypotensive Individuals With Spinal Cord Injury Phase 2
Completed NCT02006433 - Treatment of Pain and Autonomic Dysreflexia in Spinal Cord Injury With Deep Brain Stimulation N/A
Completed NCT00175682 - Prazosin Vibrostimulation Autonomic Dysreflexia and Spinal Cord Injury Study N/A
Completed NCT02298660 - Botox for Neurogenic Detrusor Overactivity and the Prevention of Autonomic Dysreflexia Following SCI Phase 4