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Clinical Trial Summary

A single arm, open-label pilot study is designed to determine the safety and effectiveness of CD19 CAR NK cells in patients with autoimmune diseases. 36-72 patients are planned to be enrolled in the dose-escalation trial. The primary objective of the study was to evaluate the safety and feasibility of CD19 CAR-NK cells for the treatment of patients with autoimmune diseases. The secondary objective is to evaluate the efficacy of CD19 CAR-NK cells in patients with autoimmune diseases.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT06464679
Study type Interventional
Source Changhai Hospital
Contact Dongbao Zhao, Dr
Phone +86-15921061314
Email dongbaozhao@163.com
Status Not yet recruiting
Phase Phase 1
Start date June 30, 2024
Completion date June 30, 2026

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