Autoimmune Diseases Clinical Trial
Official title:
Involvement of Viral Infections in the Pathogenesis of Chronic Lymphocytic Thyroiditis
Autoimmune diseases represent a heterogeneous group of pathologies whose etiopathogenic
mechanisms are most often unknown. Autoimmune diseases are the leading cause of morbidity
and mortality in young women and autoimmune thyroid diseases are the most common.
Viral infections are the main environmental factors suspected of triggering autoimmune
diseases. Several viruses are certainly involved, all of which are possibly capable of
triggering an autoimmune response. However, the precise identification of the viruses
involved remains to be established.
It has been shown for the first time by the 2005 PHRC that enteroviral RNA is present in
perioperative specimens of thyroid tissue. However, this case-control study did not show any
difference between the thyroid group and the group other thyroid pathologies It has been
recently published that Parvovirus is possibly involved in thyroiditis: the parvoviral
genome is present in the thyroid tissue of Hashimoto thyroiditis operated and more precisely
is present within the thyrocytes itself.
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