Associative Memory in Adults With an Autism Spectrum Disorder

Autistic Disorder Clinical Trial

— MEM-T2A  

Official title:

The Associative Memory in Autism Spectrum Disorders Without Intellectual Disability

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT02279680
• Other study ID #: 2013-AO1800-45
• Status: Recruiting
• Phase: N/A
• First received: June 23, 2014
• Last updated: October 28, 2014
• Start date: June 2014
• Est. completion date: December 2016

Study information

• Verified date: October 2014
• Source: University Hospital, Caen
• Contact: Bérengère GUILLERY-GIRARD, MCU
• Phone: 0231064347
• Email: berengere.guillery[@]unicaen.fr
• Is FDA regulated: No
• Health authority: France: Agence Nationale de Sécurité du Médicament et des produits de santé
• Study type: Interventional

Clinical Trial Summary

The objective of this multidisciplinary project is to explore the deficit of associative memory in ASD (Autistic Spectrum Disorder) that could result from abnormal brain connectivity. The hypothesis of abnormal functioning of the fronto-hippocampal network has been evocated but has never been tested. Hence, the present project will include two complementary assessments conducted on a group of adults aged from 18 to 30 with ASD compared to a control group matched in chronological age and intellectual quotient. The first assessment is devoted to the study of associative memory and its EEG correlates and the second focused on the investigation of perceptual strategies related to associative memory using the technique of Eye-tracking. Both behavioral and imaging data would provide new insights on the relationship between perception and memory in ASD.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 40
• Est. completion date: December 2016
• Est. primary completion date: December 2015
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years to 30 Years

Eligibility

Inclusion Criteria:

• Adult between 18 and 30 years old

• right handed

• affiliated to the french national health care system

• ASD only for the group of patients

Exclusion criteria :

• mental retardation

• schizophrenia

• ADHD

• brain injury with lost of consciousness

• neurological disease

Study Design

Allocation: Non-Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Health Services Research

Related Conditions & MeSH terms

• Autistic Disorder
• Child Development Disorders, Pervasive

Intervention

Device:
• Electroencephalography

Behavioral:
• Neuropsychological assesments

Locations

Country	Name	City	State
France	UMR1077 Inserm/EPHE/UCBN	Caen

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital, Caen

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The associative memory index		2 years	No
Secondary	theta and gamma oscillations during the associative memory task		2 years	No