Atypical Ductal Hyperplasia Clinical Trial
Official title:
Role of Contrast Enhanced Spectral Mammography to Predict Upgrade Rates of Biopsy Proven Atypical Ductal Hyperplasia
This research study is studying whether contrast enhanced mammography can predict if atypical
ductal hyperplasia will progress to cancer.
The device involved in this study is:
-Contrast enhanced mammography
This research study is a Pilot Study, which is the first time investigators are examining
this study device for this purpose.
Atypical ductal hyperplasia (ADH) is a common diagnosis after breast biopsy. Although it is
not cancer itself, ADH can become breast cancer in some cases. As a result, surgery is
performed to remove ADH to make sure it doesn't progress to cancer. In many cases, no cancer
is found during the surgery.
Previous studies have shown that breast MRI may be able to predict which areas of ADH will be
cancer at the time of surgery. This would help prevent unnecessary surgery in some patients.
Contrast enhanced mammography is a new type of mammogram that is already being used in
clinical practice to help find breast cancer. Similar to breast MRI, it uses contrast
material combined with the mammogram to highlight areas that might be breast cancer and that
could be missed on the mammogram alone. Contrast material is a dye or other substance that
helps show abnormal areas within the body.
Studies have shown the contrast enhanced mammography has a similar ability to find breast
cancer as breast MRI.
The investigators purpose is to see whether contrast enhanced mammography can predict which
areas of ADH will become breast cancer at the time of surgery. The investigators believe this
will help prevent unnecessary surgery in many with women with the diagnosis of ADH.
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