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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT06002854
Other study ID # NO.F.2-81/2022-GENL/252/JPMC
Secondary ID
Status Completed
Phase Phase 2
First received
Last updated
Start date August 1, 2022
Est. completion date February 1, 2023

Study information

Verified date June 2023
Source Jinnah Postgraduate Medical Centre
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Microneedling with topical INSULIN is a simple, effective tool for building body's new collagen layers and thus an alternative to all erosive techniques such as lasers, peels. The skin responds to fine punctures with the release of growth factors. 8 It is a safe procedure that can be performed in the office without complications, with a good cost-benefit because it is economically viable without any effect on patient's daily activities. 9


Recruitment information / eligibility

Status Completed
Enrollment 50
Est. completion date February 1, 2023
Est. primary completion date December 1, 2022
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 20 Years to 50 Years
Eligibility Inclusion Criteria: - postacne atrophic scars = 2 on Goodman and Baron's acne scar-grading system - Either gender. - Age 20-50 years. Exclusion Criteria: - lactation and pregnancy - skin cancers and infection - photosensitivity like SLE ,XP - use of RETINOIDS in last 6 months.

Study Design


Related Conditions & MeSH terms


Intervention

Drug:
PRP( platelet rich plasma) and Insulin human
Microneedling with autologus PRP reduces inflammationin acne scars. Insulin human is a new topical drug which is used nowadays for acne scars as it is more effective in producing collagen formation as well as new blood vessel formation

Locations

Country Name City State
Pakistan JPMC Karachi Sindh

Sponsors (1)

Lead Sponsor Collaborator
Jinnah Postgraduate Medical Centre

Country where clinical trial is conducted

Pakistan, 

Outcome

Type Measure Description Time frame Safety issue
Primary Efficacy of Topical Insulin R with microneedling versus Platelets rich plasma in atrophic acne scars Efficacy will be assessed by using Goodman and Baron Qualitative Scar Grading System Efficacy will be assesed upto 4 months.
See also
  Status Clinical Trial Phase
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Completed NCT02643628 - A Pilot Study to Evaluate the Safety and Effectiveness of Microneedling and Bellafill to Treat Facial Acne Scars N/A
Recruiting NCT05995340 - ELAPR002f Injectable Gel in the Treatment of Atrophic Acne Scars Phase 3
Active, not recruiting NCT01773343 - Treatment of Atrophic Acne Scars With a Fractional CO2 Laser at 1 Versus 3 Months Intervals N/A
Completed NCT02145364 - Ultherapy® for the Treatment of Acne Scars N/A
Completed NCT02735421 - Adapalene 0.3% - Benzoyl Peroxide 2.5% Gel and Risk of Formation of Atrophic Acne Scars Phase 4
Completed NCT05028283 - Treatment of Atrophic Post Acne Scars by Fat Grafting N/A