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Clinical Trial Summary

Many methods utilize for acne scar treatment including laser, cosmetic filler, microneedling, local tumescent, Subcision and chemical peels. These procedures can be used individually or as a combination therapy. Combining procedures give better results. In our study we will try in the period from March 2024 to March 2026, to assess the efficacy of combination of scar subcision with platelet rich plasma, Polydioxanone mono threads or fractional Carbon dioxide laser in the treatment of severe atrophic acne scars with 1:1:1 ratios and to compare between these modalities regarding safety and efficacy.


Clinical Trial Description

This is a prospective controlled trial that will be conducted at Dermatology, venereology, and andrology Department, Al-Azhar university hospital, Assiut, in the period from March 2024 to March 2026, to assess the efficacy of combination of scar subcision with platelet rich plasma , polydioxanone mono threads or fractional carbon dioxide laser in the treatment of severe atrophic acne scars with 1:1:1 ratios and to compare between these modalities regarding safety and efficacy ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06227481
Study type Interventional
Source Al-Azhar University
Contact Ahmed O Hassan
Phone 1155162310
Email alproff2@gmail.com
Status Not yet recruiting
Phase Phase 2
Start date March 1, 2024
Completion date March 31, 2026

See also
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Recruiting NCT04580758 - Fractional CO2 Laser Combined With PRP Fluid Versus Gel in Treatment of Acne Scars Early Phase 1
Completed NCT01559922 - Use of Artefill® for Moderate to Severe Atrophic Acne Scar Correction Phase 3
Completed NCT04740268 - Straberi Microneedling For Atrophic Acne N/A
Completed NCT02646917 - SkinPen Efficacy on Acne Scars on the Face and/or Back N/A